Designing a Novel Multiepitope Vaccine from the Human Papilloma Virus E1 and E2 Proteins for Indonesia with Immunoinformatics and Molecular Dynamics Approaches
Rizarullah,
Reza Aditama,
Ernawati Arifin Giri-Rachman
et al.
Abstract:One of the deadliest malignant cancer in women globally
is cervical
cancer. Specifically, cervical cancer is the second most common type
of cancer in Indonesia. The main infectious agent of cervical cancer
is the human papilloma virus (HPV). Although licensed prophylactic
vaccines are available, cervical cancer cases are on the rise. Therapy
using multiepitope-based vaccines is a very promising therapy for
cervical cancer. This study aimed to develop a multiepitope vaccine
based on the E1 and E2 proteins of HP… Show more
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