Abstract:Although used on a regular basis, local anaesthetics fail in places where inflammation is present, a problem for routine dental care. Intrinsic factors of the inflammatory process prevent anaesthetics from performing their function, at safe doses. The encapsulation of local anaesthetics in nanostructured lipid carriers (NLC) produces formulations with good physicochemical characteristics and improved anaesthetic effect. In that sense we developed an NLC formulation for articaine (ATC), a local anaesthetic with… Show more
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