Design two large conjugate triazolopyrimidine analogs and apply them to detect 2,4,6-trinitrophenol

Hydrogen bond directed high-fidelity optical detection of picric acid: A single driver on diverse roads towards the same destiny

“…10) was employed in the exclusive detection of PA in water as well as in DMF. 94 Unlike other common NACs, PA displayed considerable quenching of the emission intensity of 50 at 435 nm and efficiently detected PA at the sub-micromolar level (LOD = 0.025 μM in DMF and 0.44 μM in water). In addition, the fluorescence responses remained unchanged over a wide pH range (pH = 2–12).…”

Supramolecular assemblies of Zn(ii) complexes with a D–π–A ligand for sensing specific organic molecules

“…S21 †). [39][40][41][42] The upward trend K sv of 3 > 2 > 1 for sensing TNP is interesting as this is the reverse order of the number of π-π interaction types, i.e. 1 > 2 > 3 (Fig.…”

Recent Synthetic and Biological Developments on 1,2,4‐Triazolopyrimidines

“…The author utilized 3-(4-methoxyphenyl)-1H-1,2,4-triazol-5-amine (41) and unsaturated ketones 42 a-b as starting precursors at the temperature of 120 °C in DMF and triethylamine as base catalyst (Scheme 8). [72] The 2,5-bis(4-methoxyphenyl)-7-phenyl- [1,2,4] triazolo [1,5-a]pyrimidine (43 b) in the presence of trinitrophenol shows the fluorescence quenching at 435 nm with the decrease in quantum yield from 0.53 to 0.12 due to protonation of the nitrogen atom and from hydrogen-bonding. The limit of detection was found to be 0.025 μM in DMF and 0.44 μM in water.…”