Design, synthesis, X-ray analysis, and biological screening of new oxime and enaminone thiazoline-2-thione derivatives

Recent advances in the synthesis and utility of thiazoline and its derivatives

“…Asiri et al 138 developed a synthetic methodology to obtain twelve 2-thione analogues of thiazoline ( Scheme 44 ). The compounds thus synthesized were characterized by spectroscopic experiments, IR measurements, X-ray and elemental analysis.…”

“…Compounds incorporating the thiazoline moiety have been associated with diverse biological effects, including antimicrobial activity, underscoring their biomedical importance. [135][136][137] Asiri et al 138 developed a synthetic methodology to obtain twelve 2-thione analogues of thiazoline (Scheme 44). The compounds thus synthesized were characterized by spectroscopic experiments, IR measurements, X-ray and elemental analysis.…”

Thione Derivatives as Medicinally Important Compounds

“…[129] Recently, Asiri et al disclosed the synthesis and biological activities of thiazoline-2-thione derivatives. [130] The synthetic strategy used for the preparation of thiazoline-2-thiones derivatives is outlined in Scheme 28 and Scheme 29. The Compound thiazoline-2-thione 109 was synthesized at room temperature by stirring 3-chloropentane-2,4-dione with aniline and carbon disulfide in ethanol.…”

“…[129] Recently, Asiri et al disclosed the synthesis and biological activities of thiazoline-2-thione derivatives. [130] The synthetic strategy used for the preparation of thiazoline-2-thiones derivatives is outlined in Scheme 28 and Scheme 29.…”