Abstract:The benzimidazole scaffold is an important pharmacophore and one of the preferred structures in medicinal chemistry due to the wide range of biological activities of its derivatives. Here in this article, the synthesis of two series of compounds, namely bis(thiobenzimidazol-2-yl)methane derivatives and analogs (4a-e) and bis(benzimidazol-2-yl)dithiol derivatives and analogs (5a-e) are described. These compounds were synthesized by first designing 2-mercaptobenzimidazole derivatives and analogs (2a-e) by action… Show more
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