Design, synthesis, antibacterial evaluation of isopropylamine linked with different substituted phenol and piperazine novel derivatives
Wen‐Hang Wang,
Zhu‐Rui Li,
Dan‐Xue Zhu
et al.
Abstract:BACKGROUNDXanthomonas oryzae pv. oryzae (Xoo) is often considered one of the most destructive bacterial pathogens causing bacterial leaf blight (BLB), resulting in significant yield and cost losses in rice. In this study, a series of novel derivatives containing the isopropanolamine moiety linked to various substituted phenols and piperazines were designed, synthesized and screened.RESULTSAntibacterial activity results showed that most compounds had good inhibitory effects on Xoo, among which compound W2 (EC50… Show more
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