Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine

Su, Shiwei; Chen, Liqing; Yang, Menglan; Liang, Dan; Ke, Bixia; Liu, Zhongqiu; Ke, Changwen; Liao, Guochao; Liu, Liang; Luo, Xiang

doi:10.1039/d2md00298a

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RSC Med. Chem.

2023

DOI: 10.1039/d2md00298a

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Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine

Shiwei Su

Liqing Chen

Menglan Yang

et al.

Abstract: Toll-like Receptor 4 (TLR4) is a reliable target for the development of vaccine adjuvant. To identify novel TLR4 ligands with improved immunological properties and used as adjuvants for RBD-hFc based...

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Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine

Abstract: Toll-like Receptor 4 (TLR4) is a reliable target for the development of vaccine adjuvant. To identify novel TLR4 ligands with improved immunological properties and used as adjuvants for RBD-hFc based...

Cited by 0 publications

References 30 publications

No citations

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