“…Rotundic acid (RA), a plant-derived and ursane-type pentacyclic triterpene acid, was identified as a major active ingredient of IRC and has been shown to exert extensive pharmacological effects, including antimicrobial [ 3 , 4 ], anti-inflammatory [ 5 ], anticancer [ [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] ], and lipid-decreasing effects [ 14 ]. It has also been proven to alleviate type 2 diabetes and its complications by improving the composition of the gut microbiota [ 15 ].…”