New J. Chem.
 2024
DOI: 10.1039/d3nj05743g
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Design, synthesis, and evaluation of 1,4-naphthoquinone-chromene hybrids as potential anti-K562 and A549 agents

Wen-Hui Zhang,
Bo Zhang,
Bo-Wen Pan
et al.

Abstract: Two series of 1,4-naphthoquinone-chromone hybrids 4a (4aa-4ao) and 4b (4ba-4bq), were designed, synthesized and evaluated as antitumor agents. The most compounds exhibited moderate to excellent cytotoxicity to tumor cells (K562...

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