Design, synthesis, and biological evaluation of novel benzimidazolyl isoxazole derivatives as potential c-Myc G4 stabilizers to suppress c-Myc transcription and myeloma growth

Design, synthesis, and activity evaluation of 2-iminobenzimidazoles as c-Myc inhibitors for treating multiple myeloma

“…Virtually, we have been dedicating ourselves to seeking and discovering newer and more potential c-Myc inhibitors [ [31] , [32] , [33] , [34] , [35] ]. Recently, we discovered a new 2-iminobenzimidazole compound, XYA1353 ( Fig.…”