Abstract:Background:
Although transplantation, surgical resection, and tumor ablation are treatment options available following early diagnosis of HCC, their efficacy is restricted due to poor prognosis and high recurrence rates. Hence, small molecules with high selectivity and bioactivity are urgently required.
Objective:
This study presents the synthesis of a series of new triazolothiadiazole derivatives (1a-3j) with NSAID moieties and their cytotoxic bioactivities.
Methods:
The new synthetic derivatives (1-… Show more
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