Design, Synthesis and Biological Activity of Myricetin Derivatives Containing 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazole

Abstract

A series of myricetin derivatives containing 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole moiety were designed and synthesized using myricetin as the starting material through active splicing strategy. All target compounds were characterized by 1 H NMR, 13 C NMR and high-resolution mass spectra (HRMS). Single crystal X-ray diffraction experiments were carried out 有机化学 研究论文 1526 http://sioc-journal.cn/