Design, synthesis and biological activity against estrogen receptor-dependent breast cancer of furo[1]benzofuran derivatives

Jin, Liping; Zhang, Chao; Xie, Qian; Xu, Jing; Wang, Lin; Yang, Lingchen; Huang, Er-Fang; Wan, David Chi Cheong; Hu, Chun

doi:10.1016/j.arabjc.2022.104227

Cited by 2 publications

(3 citation statements)

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“…52 Earlier methods also involved the treatment of hydroxy-substituted acetophenones/halogen-substituted acetophenones with ketones to attain the synthesis of benzofuran heterocycles. 53,54 Many review articles covering the versatile synthetic approaches for benzofuran synthesis have been published by different research groups. 55, 56 Bhargava et al in 2017 and later Miao et al in 2019 presented reviews on the synthetic pathways toward the synthesis of medicinally important benzofurans and their derivatives.…”

Section: Introductionmentioning

confidence: 99%

“…Considering the medicinal applications of benzofuran derivatives, several methods are reported each year contributing toward their synthesis. − Most common methods include the reaction of salicylaldehyde with ethylchloroacetate/ethylbromoacetate − or with α-haloketone/acetone . Earlier methods also involved the treatment of hydroxy-substituted acetophenones/halogen-substituted acetophenones with ketones to attain the synthesis of benzofuran heterocycles. , …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Comprehensive Review on Benzofuran Synthesis Featuring Innovative and Catalytic Strategies

Mushtaq,

Zahoor,

Ahmad

et al. 2024

ACS Omega

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Benzofurans have intrigued both pharmaceutical researchers and chemists owing to the medicinal usage of their derivatives against copious diseasecausing agents (i.e., bacteria, viruses, and tumors). These heterocyclic scaffolds are pervasively encountered in a number of natural products and drugs. The everincreasing utilization of benzofuran derivatives as pharmaceutical agents persuaded the chemists to devise novel and facile methodological approaches to assemble the biologically potent benzofuran nucleus. This review summarizes the current developments regarding the innovative synthetic routes and catalytic strategies to procure the synthesis of benzofuran heterocycles with their corresponding mechanistic details, reported by several research groups during 2021−2023.

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