Design, synthesis and antiviral activity of novel quinazolinones

CuBr/Et3N‐Promoted Reactions of 2‐Aminobenzamides and Isothiocyanates: Efficient Synthesis of Novel Quinazolin‐4(3H)‐ones

“…Quinazolin‐4(3 H )‐ones are biologically important compounds due to their continued application in medicinal chemistry . At this juncture, medicinal properties, such as antiulcer , anticancer , anti‐inflammatory , anticonvulsant , hypolipidemic , antifungal , antiviral , and anti‐coccidial , have been the center of attention for medicinal chemists. Therefore, several procedures have been reported for the synthesis of quinazolin‐4(3 H )‐ones .…”

Comparative Studies of Interactions between Fluorodihydroquinazolin Derivatives and Human Serum Albumin with Fluorescence Spectroscopy

“…Heterocyclic structures play a pivotal role in many pharmaceutical, agrochemical, and veterinary products, like quinazolines. An increasing number of quinazoline derivatives have been reported to possess antibacterial [15], anticancer [16], antitubercular [17], anti-HIV [18], antifungal [19], analgesic [20], anti-inflammatory [21], anticonvulsant [22], antiparkinson [23], anthelmintic [24], anti-histaminic [25], and antihypertensive activities [26]. Much attention has been focused on their structures and bioactivity.…”

Untitled

“…Quinazolin-4(3H)-one represents a versatile lead molecule for the design of potential bioactive agents [1][2][3][4][5][6][7] and the pharmaceuticals containing quinazolinone nucleus show varied biological activities as different substitution patterns results in diverse biological properties [8][9][10] . Number of quinazoline derivatives with different substitutions at 2,3,4,6 positions have been reported and studied as antitumor 11 , antibacterial 12 , anticonvulsant 13 , antimalarials 14 and antiviral agents 15 as shown in Table 1.…”