Design, Synthesis, and Antifungal Evaluation of Diverse Heterocyclic Hydrazide Derivatives as Potential Succinate Dehydrogenase Inhibitors
Yiliang Chen,
Hao Liu,
Jiahao Wang
et al.
Abstract:Plant pathogenic fungi pose a significant
threat to agricultural
production, necessitating the development of new and more effective
fungicides. The ring replacement strategy has emerged as a highly
successful approach in molecular design. In this study, we employed
the ring replacement strategy to successfully design and synthesize
32 novel hydrazide derivatives containing diverse heterocycles, such
as thiazole, isoxazole, pyrazole, thiadiazole, 1,3,4-oxadiazole, 1,2,4-oxadiazole,
thiophene, pyridine, and pyr… Show more
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