Design, synthesis and anticancer activity of novel hybrid compounds between benzofuran and N-aryl piperazine

The crystal structure of 1,4-dinitroso-2,3,5,6-tetraacetoxy-piperazine, C12H16N4O10

“…The asymmetric unit contains a half molecule and the whole molecule is sited on a crystallographic inversion centre. The nitroso group is disordered over two positions, with refined occupancies of 0.581 7and 0.419 (7).…”

“…Piperazine derivatives have important applications in the fields of medicinal chemistry and materials [4][5][6][7][8][9][10]. The molecular structure of the title compound (cf.…”

The crystal structure of 1,4-dinitro-2,3,5,6-tetraacetoxy-piperazine, C12H16N4O12

“…Piperazine is a typical heterocyclic compound, and its derivatives have important applications in the fields of medicines and materials [4][5][6][7][8][9]. The molecular structure of the title compound (cf.…”

Synthesis,Spectroscopic Investigation, Anti-Bacterial and Antioxidant Activites of Some New Azo-Benzofuran Derivatives

“…It is a main scaffold structure in many of natural and drug compounds [5]. Benzufurans have valuable biological properties such as, antitumor [6,7], anti-inflammation [8]3d, 3e, 9c and 9d -were assessed for their anti-inflammatory activity and ulcerogenic liability in vivo. The 3-(pyridin-3-yl, anti-microbial [9,10], anti-proliferative effects [11], and antioxidant [12][13][14].…”