Design strategies for optimizing holographic optical tweezers set-ups

Martı́n-Badosa, Estela; Montes-Usategui, Mario; Carnicer, Artur; Andilla, Jordi; Pleguezuelos, Encarnacion; Juvells, Ignasi

doi:10.1088/1464-4258/9/8/s22

Cited by 64 publications

(48 citation statements)

References 30 publications

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“…Multiple optical traps are created by using diffractive optical elements to split and steer the light from a single beam between multiple traps, which can easily become dynamic by using liquid crystal devices, such as SLMs, to display phase-only holograms (Curtis et al 2002). The working principles of HOTs generated from an SLM are illustrated in figure 1g (Martin-Badosa et al 2007). A continuous-wave TEM 00 laser beam is first expanded and then collimated by two lenses.…”

Section: Multiple Trapsmentioning

confidence: 99%

Optical tweezers for single cells

Zhang

Liu

2008

J. R. Soc. Interface.

661

441

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Optical tweezers (OT) have emerged as an essential tool for manipulating single biological cells and performing sophisticated biophysical/biomechanical characterizations. Distinct advantages of using tweezers for these characterizations include non-contact force for cell manipulation, force resolution as accurate as 100 aN and amiability to liquid medium environments. Their wide range of applications, such as transporting foreign materials into single cells, delivering cells to specific locations and sorting cells in microfluidic systems, are reviewed in this article. Recent developments of OT for nanomechanical characterization of various biological cells are discussed in terms of both their theoretical and experimental advancements. The future trends of employing OT in single cells, especially in stem cell delivery, tissue engineering and regenerative medicine, are prospected. More importantly, current limitations and future challenges of OT for these new paradigms are also highlighted in this review.

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Section: Multiple Trapsmentioning

confidence: 99%

Optical tweezers for single cells

Zhang

Liu

2008

J. R. Soc. Interface.

661

441

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“…10 Traps were generated and controlled via a LabView programme which was based on the commonly used "superposition of gratings and lenses" (SGL) algorithm.…”

Section: All-optical Manipulation Of Photonic Membranesmentioning

confidence: 99%

All-optical manipulation of photonic membranes

et al. 2016

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Photonic membranes (PMs) are thin, highly-flexible, membranes which can be imbued with specific photonic functionalities when used to play host to plasmonic features. 1-3 PMs can then take that photonic functionality and transfer it to an external object, provided that they can be manipulated with enough precision. We demonstrate a fabrication and optical manipulation protocol that allows PMs to be manoeuvred through a microfluidic environment, and show that the trap stiffness of such a scheme is on par with current techniques. The PMs shown here are 90 nm thick, with the potential to be extremely flexible. We comment on their current deformability.

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“…5), which consists from a hand-made inverted light microscope with Zeiss 100× objective (1.32 NA, oil immersion, Plan-Apochromat), a reflective LCoS-SLM (Holoeye LCR-2500, twisted nematic, 8-bit grayscale signal, pixel size δ = 19 µm) operating in phase-only modulation, and Nd:YAG laser with wavelength λ = 532 nm and 400 mW. Theory and experimental implementation of such systems are studied in [19] and [20], to name a few. The CGH is addressed onto a phase-only SLM that modulates a collimated laser beam.…”

Section: Experimental Implementationmentioning

confidence: 99%

“…Because of such a filtering process the maximum beam output power is about one half of the one corresponding to the input collimated beam. Wavefront distortion φ ab arising from the SLM non-flatness, mainly astigmatism and spherical aberration, was calibrated following the suggestions reported in [20]. The SLM also allows compensating the wavefront aberrations corresponding to the optical setup, see Refs.…”

Section: Experimental Implementationmentioning

confidence: 99%

Microparticle movements in optical funnels and pods

Rodrigo¹,

Caravaca-Aguirre

Alieva

et al. 2011

Opt. Express

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Three-dimensional microparticle movements induced by laser beams with a funnel-and tubular pod-like structure, in the neighbourhood of the focal plane of an optical trapping setup, are experimentally studied. The funnel and pod beams constructed as coherent superpositions of helical Laguerre-Gaussian modes are synthesized by a computer generated hologram using a phase-only spatial light modulator. Particle tracking is achieved by in-line holography method which allows an accurate position measurement. It is experimentally demonstrated that the trapped particle follows different trajectories depending on the orbital angular momentum density of the beam. In particular applying the proposed pod beam the particle rotates in opposite directions during its movement in the optical trap. Possible applications of these single-beam traps for volumetric optical particle manipulation are discussed.

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Design strategies for optimizing holographic optical tweezers set-ups

Cited by 64 publications

References 30 publications

Optical tweezers for single cells

Optical tweezers for single cells

All-optical manipulation of photonic membranes

Microparticle movements in optical funnels and pods

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