Design, selection and characterization of novel glasses and glass-ceramics for use in prosthetic applications

Baino, Francesco; Marshall, Martyn; Kirk, Nicholas; Vitale-Brovarone, C.

doi:10.1016/j.ceramint.2015.09.094

Cited by 43 publications

(26 citation statements)

References 43 publications

(61 reference statements)

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“…The white, shiny aspect of the heat-treated S57A7 coating (Fig. 6b) suggests its glass-ceramic nature, in accordance to previous results reported elsewhere [32]. Small-and large-size cups (Fig.…”

Section: Dense Coating (Interlayer)supporting

confidence: 77%

“…Full characterization of S57A7 and S50B2 glasses, including the glass-ceramic products obtained from them after sintering, has been reported elsewhere [32].…”

Section: Characterisationmentioning

confidence: 99%

“…This technique is generally recognized as a highly effective and versatile method to process bioactive glasses in the form of bone-like porous scaffolds [32], and early results attained in previous studies by our research team demonstrated the suitability of this method to fabricate trabecular coatings on flat prosthetic implants [26,27]. In order to effectively apply the trabecular coating to a "real" bioceramic cup that is to be used in hip joint surgery, there were two key questions to answer: (i) how to impart a shell-like shape to the porous polymeric template?, and (ii) how to remove the excess slurry from the pores of the polymeric foam in this particular configuration?…”

Section: Fabrication Of the Trabecular Coatingmentioning

confidence: 99%

“…Criteria of design and selection as well as the characterization of these glasses are reported elsewhere [32]. S57A7 and S50B2 were individually manufactured and the mixed high-purity raw materials (oxides and carbonates) added to platinum crucibles for subsequent melting.…”

Section: Starting Materialsmentioning

confidence: 99%

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Novel full-ceramic monoblock acetabular cup with a bioactive trabecular coating: design, fabrication and characterization

Baino

Minguella-Canela

Kirk

et al. 2016

Ceramics International

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Over the last 25 years, the philosophy behind an optimal fixation of orthopaedic implants to hard tissues progressively evolved towards "bone-conservative" solutions in order to minimize bone resection/loss and maximize tissue-implant integration. Hence, the researchers' attention moved from "traditional" fixation of the prosthesis to host bone by using screws or acrylic cement to new strategies based on physico-chemical bonding and surface modification of the implant. This research work explores the feasibility of a novel bioceramic monoblock acetabular cup for hip joint prosthesis that can be fixed to the patient's bone by means of a bone-like trabecular coating able to promote implant osteointegration. Sponge replica method was properly adapted and optimized to produce hemispherical foam-like bioactive glass-ceramic coatings that were joined to Al 2 O 3 /ZrO 2 composite cups by the interposition of a glass-ceramic interlayer. Morphological analyses by scanning electron microscopy (SEM) and micro-computed tomography revealed the good quality of joining at the different interfaces. Preliminary investigation of the mechanical properties was carried out to evaluate the suitability of the device for biomedical use. In vitro bioactive behaviour was assessed by immersion studies in simulated body fluid and evaluating the apatite formation on the struts of the trabecular coating. The concepts and findings reported in the present work can have a significant impact in the field of implantable devices, suggesting a valuable alternative to currently-applied but often suboptimal techniques for bone-prosthesis fixation.

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Section: Dense Coating (Interlayer)supporting

confidence: 77%

“…Full characterization of S57A7 and S50B2 glasses, including the glass-ceramic products obtained from them after sintering, has been reported elsewhere [32].…”

Section: Characterisationmentioning

confidence: 99%

Section: Fabrication Of the Trabecular Coatingmentioning

confidence: 99%

Section: Starting Materialsmentioning

confidence: 99%

See 2 more Smart Citations

Novel full-ceramic monoblock acetabular cup with a bioactive trabecular coating: design, fabrication and characterization

Baino

Minguella-Canela

Kirk

et al. 2016

Ceramics International

Self Cite

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“…For instance, Santocildes-15 Romero et al 23 have showed an increase of the cytotoxic effect of BGs dissolution by increasing 16 the amount of glass powders used and the level of strontium substitution added to the glass 17 for the treatment of osteoporosis 21 . 24 Various studies have been reported concerning the use of heat treatments in order to induce 25 crystallisation in BGs to promote changes in their physico-chemical properties [27][28][29][30][31] . For instance, 26…”

Section: Introductionmentioning

confidence: 99%

Design and Properties of Novel Substituted Borosilicate Bioactive Glasses and Their Glass-Ceramic Derivatives

Fernandes

Gentile

Moorehead

et al. 2016

Crystal Growth & Design

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1Three novel borosilicate bioactive glasses (BBGs) of general formula of 0.05Na2O0.35x 2 0.20B2O30.40SiO2 (molar ratio, where x = MgO or CaO or SrO) were prepared and used to 3 investigate the effect of crystallisation on their properties including cytotoxicity. The three post-4 melt compositions were determined using X-ray fluorescence spectroscopy and crystallisation 5 events were studied using differential thermal analysis and x-ray diffraction. This information was 6 used to determine heat treatments to prepare glass-ceramics by controlled crystallisation. X-ray 7 diffraction analysis and Fourier transform infrared spectroscopy showed that, after higher heat 8 treatment temperatures (800-900 ºC), borosilicate bioactive glass-ceramics (BBGCs) contained 9 mainly borate and silicate crystalline phases. Specifically, BBG-Mg, BBG-Ca and BBG-Sr glass-10 ceramics detected the presence of magnesium silicate-Mg2(SiO3)2 and magnesium borate-Mg2B2O5; 11 wollastonite-2M-CaSiO3 and calcium borate-Ca(BO2)2; and strontium silicate-SrSiO3 and strontium 12 borate-Sr2B2O5, respectively. In vitro cytotoxicity tests were performed using the mouse fibroblast 13 cell line (L929). Glass and glass ceramic at concentrations lower than 50 mg/ml did not exhibit any 14 level of cytotoxicity when compared with the control. However, quantitative evaluation indicated 15 that greater cell growth occurred in the presence of materials with crystalline phases. Control of 16BBGs crystallisation may therefore be used to influence the biocompatibility of these glass-ceramic 17 systems. 18

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Laser Cladding and Laser Direct Glass Deposition of Bioactive Glass and Glass‐Ceramics

Comesaña

Val

Quintero

et al. 2022

Bioactive Glasses and Glass‐Ceramics

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Design, selection and characterization of novel glasses and glass-ceramics for use in prosthetic applications

Cited by 43 publications

References 43 publications

Novel full-ceramic monoblock acetabular cup with a bioactive trabecular coating: design, fabrication and characterization

Novel full-ceramic monoblock acetabular cup with a bioactive trabecular coating: design, fabrication and characterization

Design and Properties of Novel Substituted Borosilicate Bioactive Glasses and Their Glass-Ceramic Derivatives

Laser Cladding and Laser Direct Glass Deposition of Bioactive Glass and Glass‐Ceramics

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