Design rules applied to silver nanoparticles synthesis: A practical example of machine learning application.

Furxhi, Irini; Faccani, Lara; Zanoni, Ilaria; Brigliadori, Andrea; Vespignani, Maurizio; Costa, Anna Luisa

doi:10.1016/j.csbj.2024.02.010

Cited by 2 publications

(1 citation statement)

References 103 publications

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“…Supplementary algorithms have been implemented to predict KPI1 merging data from the literature [88] . By leveraging regression predictive models, it is feasible to forecast PCFs from synthesis parameters (such as synthesis duration, scale, and the choice of capping agent), thus enabling the rational design of NMs [89] . It is outside the scope of this study to outline the various models available in the literature for each dimension.…”

Section: Discussionmentioning

confidence: 99%

A roadmap towards safe and sustainable by design nanotechnology: Implementation for nano-silver-based antimicrobial textile coatings production by ASINA project

Furxhi,

Perucca,

Koivisto

et al. 2024

Computational and Structural Biotechnology Journal

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Section: Discussionmentioning

confidence: 99%

A roadmap towards safe and sustainable by design nanotechnology: Implementation for nano-silver-based antimicrobial textile coatings production by ASINA project

Furxhi,

Perucca,

Koivisto

et al. 2024

Computational and Structural Biotechnology Journal

Self Cite

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Re-designing nano-silver technology exploiting one-pot hydroxyethyl cellulose-driven green synthesis

Blosi,

Brigliadori,

Ortelli

et al. 2024

Front. Chem.

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Re-designing existing nano-silver technologies to optimize efficacy and sustainability has a tangible impact on preventing infections and limiting the spread of pathogenic microorganisms. Advancements in manufacturing processes could lead to more cost-effective and scalable production methods, making nano-silver-based antimicrobial products more accessible in various applications, such as medical devices, textiles, and water purification systems. In this paper, we present a new, versatile, and eco-friendly one-pot process for preparing silver nanoparticles (AgNPs) at room temperature by using a quaternary ammonium salt of hydroxyethyl cellulose (HEC), a green ingredient, acting as a capping and reducing agent. The resulting nano-hybrid phase, AgHEC, consists of AgNPs embedded into a hydrogel matrix with a tunable viscosity depending on the conversion grade, from ions to nanoparticles, and on the pH. To investigate the synthesis kinetics, we monitored the reaction progress within the first 24 h by analyzing the obtained NPs in terms of particle size (dynamic light scattering (DLS), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM)), Z-potential (ELS), surface plasmon resonance (UV-VIS), crystallographic phase (XRD), viscosity, and reaction yield (inductively coupled plasma-optical emission spectrometry (ICP-OES)). To explore the design space associated with AgHEC synthesis, we prepared a set of sample variants by changing two independent key parameters that affect nucleation and growth steps, thereby impacting the physicochemical properties and the investigated antimicrobial activity. One of the identified design alternatives pointed out an improved antimicrobial activity in the suspension, which was confirmed after application as a coating on nonwoven cellulose fabrics. This enhancement was attributed to a lower particle size distribution and a positive synergistic effect with the HEC matrix.

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Design rules applied to silver nanoparticles synthesis: A practical example of machine learning application.

Cited by 2 publications

References 103 publications

A roadmap towards safe and sustainable by design nanotechnology: Implementation for nano-silver-based antimicrobial textile coatings production by ASINA project

A roadmap towards safe and sustainable by design nanotechnology: Implementation for nano-silver-based antimicrobial textile coatings production by ASINA project

Re-designing nano-silver technology exploiting one-pot hydroxyethyl cellulose-driven green synthesis

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