Design, preparation, and characterization of CS/PVA/SA hydrogels modified with mesoporous Ag<sub>2</sub>O/SiO<sub>2</sub> and curcumin nanoparticles for green, biocompatible, and antibacterial biopolymer film

Farazin, Ashkan; Mohammadimehr, Mehdi; Ghasemi, Arman; Naeimi, Hossein

doi:10.1039/d1ra05153a

Cited by 29 publications

(14 citation statements)

References 115 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fig. 3a illustrates a broad signal corresponding to the amorphous nature of the SiO 2 spheres, 34 and Fig. 3b is due to XRD patterns of the Co-Ni@HCSs.…”

Section: Resultsmentioning

confidence: 99%

Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines

2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…Fig. 3a illustrates a broad signal corresponding to the amorphous nature of the SiO 2 spheres, 34 and Fig. 3b is due to XRD patterns of the Co-Ni@HCSs.…”

Section: Resultsmentioning

confidence: 99%

Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines

2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…The same slow release of antibacterial agent obtained by Farazin et al using encapsulated Ag 2 O in SiO 2 and embedded these nanoparticles as well as curcumin into CS/PVA/SA hydrogels for antibacterial biopolymer film. 145 In other research, Wu et al fabricated chitosan-deposited layer by layer (LBL)-structured lysozyme nanofibers for long-term antibacterial activity by gradual degradation of the lysozyme, which release chitosan, hence boosting the antibacterial activity. 146 Even though a chitosan-based antibacterial sponge shows remarkable antibacterial activity, it is not capable to adhere strongly to the skin tissue leading to ineffective contact.…”

Section: Chitosan-based Biomaterials For Wound Healingmentioning

confidence: 99%

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

Budiarso,

Rini,

Tsalsabila

et al. 2023

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

Over the past decade, smart and functional biomaterials have escalated as one of the most rapidly emerging fields in the life sciences because the performance of biomaterials could be improved by careful consideration of their interaction and response with the living systems. Thus, chitosan could play a crucial role in this frontier field because it possesses many beneficial properties, especially in the biomedical field such as excellent biodegradability, hemostatic properties, antibacterial activity, antioxidant properties, biocompatibility, and low toxicity. Furthermore, chitosan is a smart and versatile biopolymer due to its polycationic nature with reactive functional groups that allow the polymer to form many interesting structures or to be modified in various ways to suit the targeted applications. In this review, we provide an up-to-date development of the versatile structures of chitosan-based smart biomaterials such as nanoparticles, hydrogels, nanofibers, and films, as well as their application in the biomedical field. This review also highlights several strategies to enhance biomaterial performance for fast growing fields in biomedical applications such as drug delivery systems, bone scaffolds, wound healing, and dentistry.

show abstract

“…Excess liquid was removed gently with a filter paper and the swelling ratio was estimated according to the following Eq. [36].…”

Section: Determination Of Swelling Percent Of Frankincense Powdermentioning

confidence: 99%

An Innovative Approach for Formulation of Rutin Tablets Targeted for Colon Cancer Treatment

2023

View full text Add to dashboard Cite

The aim of this study was the improvement of rutin solubility along with targeting its release to colon for effective treatment of colon cancer. Five formulations of compression-coated tablets were prepared with the same core composition including rutin-polyvinyl pyrrolidone K30 solid dispersion (rutin-PVP K30 SD) but differ in being coated with either frankincense alone or different combinations of frankincense with gelatin. The superior formula was selected based on the in vitro drug release then further evaluated in terms of physical properties and in vivo performance in dogs using X-ray. Moreover, in vitro cytotoxicity of rutin, rutin-PVP K30 SD, frankincense, and a mixture of rutin-PVP K30 SD with frankincense in a ratio representing their concentrations in the selected formula was assessed against human colon cancer (HCT-116) cell lines using sulforhodamine B assay. The formula (F4) with the coat consisted of 65%w/w frankincense and 35%w/w gelatin achieved acceptable in vitro controlled drug release. In vivo X-ray in dogs confirmed that F4 tablet could remain intact in the stomach and small intestine until reaching the colon. In vitro cytotoxicity revealed that mixture of rutin-PVP K30 SD with frankincense was more effective in arresting cancer cell growth than rutin or frankincense alone. Moreover, stability studies revealed that F4 tablets were physically and chemically stable. Thus, improving rutin solubility using solid dispersion technique and formulating it into frankincense-based compression-coated (F4) tablets would be a successful approach for colonic delivery of rutin with potential of improving therapeutic efficacy. Graphical Abstract

show abstract

Design, preparation, and characterization of CS/PVA/SA hydrogels modified with mesoporous Ag₂O/SiO₂ and curcumin nanoparticles for green, biocompatible, and antibacterial biopolymer film

Abstract: CS/PVA/SA hydrogels modified with mesoporous Ag2O/SiO2 and curcumin nanoparticles for antibacterial biopolymer film.

Cited by 29 publications

References 115 publications

Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines

Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

An Innovative Approach for Formulation of Rutin Tablets Targeted for Colon Cancer Treatment

Contact Info

Product

Resources

About

Design, preparation, and characterization of CS/PVA/SA hydrogels modified with mesoporous Ag2O/SiO2 and curcumin nanoparticles for green, biocompatible, and antibacterial biopolymer film

Abstract: CS/PVA/SA hydrogels modified with mesoporous Ag2O/SiO2 and curcumin nanoparticles for antibacterial biopolymer film.

Cited by 29 publications

References 115 publications

Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines

Preparation and characterization of doped hollow carbon spherical nanostructures with nickel and cobalt metals and their catalysis for the green synthesis of pyridopyrimidines

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

An Innovative Approach for Formulation of Rutin Tablets Targeted for Colon Cancer Treatment

Contact Info

Product

Resources

About

Design, preparation, and characterization of CS/PVA/SA hydrogels modified with mesoporous Ag₂O/SiO₂ and curcumin nanoparticles for green, biocompatible, and antibacterial biopolymer film