Design Optimization for a Microfluidic Crossflow Filtration System Incorporating a Micromixer

Jung, Sung-Cherl; Park, Jo Eun; Kang, Tae Gon; Ahn, Kyung Hyun

doi:10.3390/mi10120836

Cited by 15 publications

(16 citation statements)

References 48 publications

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“…The change of the channel width makes the liquid flow perpendicular to the fluid flow direction, and the bending of the microchannel makes the pressure difference inside the liquid. In this case, the method of channel bending and width variation were proposed to improve the mixing efficiency [ 30 , 31 ]. Based on the above principles, two types of microchannel structure were designed, as shown in Figure 4 .…”

Section: Resultsmentioning

confidence: 99%

Development of Rapid and High-Precision Colorimetric Device for Organophosphorus Pesticide Detection Based on Microfluidic Mixer Chip

et al. 2021

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The excessive pesticide residues in cereals, fruit and vegetables is a big threat to human health, and it is necessary to develop a portable, low-cost and high-precision pesticide residue detection scheme to replace the large-scale laboratory testing equipment for rapid detection of pesticide residues. In this study, a colorimetric device for rapid detection of organophosphorus pesticide residues with high precision based on a microfluidic mixer chip was proposed. The microchannel structure with high mixing efficiency was determined by fluid dynamics simulation, while the corresponding microfluidic mixer chip was designed. The microfluidic mixer chip was prepared by a self-developed liquid crystal display (LCD) mask photo-curing machine. The influence of printing parameters on the accuracy of the prepared chip was investigated. The light source with the optimal wavelength of the device was determined by absorption spectrum measurement, and the relationship between the liquid reservoir depth and detection limit was studied by experiments. The correspondence between pesticide concentration and induced voltage was derived. The minimum detection concentration of the device could reach 0.045 mg·L−1 and the average detection time was reduced to 60 s. The results provide a theoretical and experimental basis for portable and high-precision detection of pesticide residues.

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Section: Resultsmentioning

confidence: 99%

Development of Rapid and High-Precision Colorimetric Device for Organophosphorus Pesticide Detection Based on Microfluidic Mixer Chip

et al. 2021

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“…Several studies have focused on the implementation of static elements inside microfluidic channels to induce mixing. Among all the different configurations, ribs and staggered herringbones geometries have been successfully used in the investigation of CP (Figure 5a,b) [77,93]. Kaufman et al explored the implementation of NF and RO processes in microfluidics, optimizing system design in order to contain CP [90].…”

Section: The Pre-fouling Stagementioning

confidence: 99%

Section: Fouling: Stages and Interactionsmentioning

confidence: 99%

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Membrane Fouling Phenomena in Microfluidic Systems: From Technical Challenges to Scientific Opportunities

2021

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The almost ubiquitous, though undesired, deposition and accumulation of suspended/dissolved matter on solid surfaces, known as fouling, represents a crucial issue strongly affecting the efficiency and sustainability of micro-scale reactors. Fouling becomes even more detrimental for all the applications that require the use of membrane separation units. As a matter of fact, membrane technology is a key route towards process intensification, having the potential to replace conventional separation procedures, with significant energy savings and reduced environmental impact, in a broad range of applications, from water purification to food and pharmaceutical industries. Despite all the research efforts so far, fouling still represents an unsolved problem. The complex interplay of physical and chemical mechanisms governing its evolution is indeed yet to be fully unraveled and the role played by foulants’ properties or operating conditions is an area of active research where microfluidics can play a fundamental role. The aim of this review is to explore fouling through microfluidic systems, assessing the fundamental interactions involved and how microfluidics enables the comprehension of the mechanisms characterizing the process. The main mathematical models describing the fouling stages will also be reviewed and their limitations discussed. Finally, the principal dynamic investigation techniques in which microfluidics represents a key tool will be discussed, analyzing their employment to study fouling.

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“…Generally, these methods can be divided into two categories: active methods and passive methods [4]. Passive methods usually utilize various geometries [5–17] of microchannels and different shapes of obstacles [18–23] or grooves [24–27] placed in microchannels to disturb the laminar flow for vortex formation. Passive methods do not need external energy sources, but the channels of such methods usually need to be designed with complex structures, thereby increasing the fabrication difficulty.…”

Section: Introductionmentioning

confidence: 99%

Electrokinetic‐vortex formation near a two‐part cylinder with same‐sign zeta potentials in a straight microchannel

2020

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Vortex formation near a two-part cylinder with zeta potentials of different values but the same sign under an external DC electric field is numerically investigated in this paper. The cylinder, inserted in a straight microchannel filled with an aqueous solution, is composed of an upstream part and a downstream part. When a DC electric field is applied in the channel, under certain conditions, the vortex will form near the cylinder due to the different velocities of electroosmotic flow generated on the cylinder surface. The numerical results reveal that the larger the velocity difference of electroosmotic flow generated on the two-part cylinder and the smaller the channel width, the more conducive to vortex formation in the channel. In addition, if the zeta potential ratios of cylinder downstream part to upstream part and channel wall to cylinder upstream part are unchanged, the DC electric field strength and the zeta potential value do not affect the pattern of vortices formed in the channel. This study provides a way for vortex formation in microchannels and has the potential application in microfluidic devices.

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Design Optimization for a Microfluidic Crossflow Filtration System Incorporating a Micromixer

Cited by 15 publications

References 48 publications

Development of Rapid and High-Precision Colorimetric Device for Organophosphorus Pesticide Detection Based on Microfluidic Mixer Chip

Development of Rapid and High-Precision Colorimetric Device for Organophosphorus Pesticide Detection Based on Microfluidic Mixer Chip

Membrane Fouling Phenomena in Microfluidic Systems: From Technical Challenges to Scientific Opportunities

Electrokinetic‐vortex formation near a two‐part cylinder with same‐sign zeta potentials in a straight microchannel

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