2019
DOI: 10.3390/nano9091227
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Design of Plasmonic-Waveguiding Structures for Sensor Applications

Abstract: Surface plasmon resonance has become a widely accepted optical technique for studying biological and chemical interactions. Among others, detecting small changes in analyte concentration in complex solutions remains challenging, e.g., because of the need of distinguishing the interaction of interest from other effects. In our model study, the resolution ability of plasmonic sensing element was enhanced by two ways. Besides an implementation of metal-insulator-metal (MIM) plasmonic nanostructure, we suggest con… Show more

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Cited by 15 publications
(11 citation statements)
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“…Owing to this simple and distinctive phenomenon, SPR-based biosensors have gained extensive attention to develop label-free and real-time biosensors with minimal sample preparation procedures [ 32 , 33 , 34 , 35 , 36 ]. Furthermore, as the dimension of EVs perfectly matches the sensing depth of SPR (200 nm), SPR-based biosensors are effective for quantifying EVs from complex biologic fluids [ 37 , 38 , 39 , 40 ]. In this section, recent studies related to SPR-based exosomal detection platforms are briefly introduced.…”
Section: Surface Plasmon Resonance-based Analysis Methods For Ev Dmentioning
confidence: 99%
“…Owing to this simple and distinctive phenomenon, SPR-based biosensors have gained extensive attention to develop label-free and real-time biosensors with minimal sample preparation procedures [ 32 , 33 , 34 , 35 , 36 ]. Furthermore, as the dimension of EVs perfectly matches the sensing depth of SPR (200 nm), SPR-based biosensors are effective for quantifying EVs from complex biologic fluids [ 37 , 38 , 39 , 40 ]. In this section, recent studies related to SPR-based exosomal detection platforms are briefly introduced.…”
Section: Surface Plasmon Resonance-based Analysis Methods For Ev Dmentioning
confidence: 99%
“…Therefore, the spectral SNR [ 24 ] curve is a key factor affecting sensor performance. Vlek et al changed the sensor layer structure and the metal layer structure to enhance the resolution of the SPR sensor [ 25 ]. Maharana et al changed the prism material and metal layer material to enhance the resolution of the SPR sensor [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…[29,33] or PMMA ( [34]). Again at λ=632.8 nm the reflectance/incident angle graph displays a Fano resonance that is very sensitive to changes of the refractive index in a solution containing a chemical or a biological system to be analyzed [7,15,8,9].…”
Section: Introductionmentioning
confidence: 99%