Design of MEMS sensor for the detection of cholera and diarrehea by capacitance modulation

Karuveettil, Vineetha; Kumar, Prem; Sailaja, B. V. S.; Guha, Koushik; Sravani, K. Girija; Rao, K. Srinivasa

doi:10.1007/s00542-017-3702-4

Cited by 7 publications

(2 citation statements)

References 20 publications

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“…tool. The structure is modeled in MEMS to estimate the bio electrical properties of cells [30][31][32][33][34][35].…”

Section: Bio Electical Characterizationmentioning

confidence: 99%

Development of a MEMS-Based Biosensor for Analyzing the Bio-Electrical Characteristics of Colon Cancer Cells

shameem

2024

Preprint

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Investigating the bioelectrical characteristics of individual cells can provide important information about many aspects of cellular processes and their roles in general health and disease conditions. Comprehending these attributes at the cellular level facilitates a more intricate comprehension of physiological mechanisms and creates novel opportunities for disease detection, management, and even averting. It's fascinating to observe how new methods and technological developments are allowing us to learn more about the intricacies of cellular biology and how they relate to human health. Since cancer cells have slightly lower capacitance and resistance values, the bioelectrical properties could be used as biomarkers for early cancer identification. Measurements were conducted on the capacitance and resistance of individual normal cell lines (IEC-6), and highly-invasive malignant (SW480) colon cancer cells using MEMS sensors during simulations. Normal cell resistance is 318kΩ, while normal cell capacitance is 8.12nF. These values differ from those of cancer cells, which have variable resistance and capacitance values (246kΩ and 3.91nF for SW480). At a frequency range of 200 Hz to 2 MHz significant difference is observed in impedance magnitude response values between normal cells (7.7 MΩ to 62kΩ) and cancer cells (7.1 MΩ to 54.9kΩ).

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“…tool. The structure is modeled in MEMS to estimate the bio electrical properties of cells [30][31][32][33][34][35].…”

Section: Bio Electical Characterizationmentioning

confidence: 99%

Development of a MEMS-Based Biosensor for Analyzing the Bio-Electrical Characteristics of Colon Cancer Cells

shameem

2024

Preprint

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“…This research presents a series of unique integrated capacitive sensing and actuation technologies based on nanostructures. Capacitance fluctuations caused by the deflection of bimetallic cantilevers loaded by linear or nonlinear electrostatic forces and thermal bending forces are used in sensors and actuators (Vineetha et al, 2018a), (Hegner and Arntz, 2003). The static behaviour of nano cantilever beams was also investigated (Katta et al, 2020).…”

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confidence: 99%

Mathematical Modelling and Analysis of Temperature Effects in NEMS Based Bi-Metallic Cantilever for Molecular Biosensing Applications

Katta¹,

Sandanalakshmi²

2022

KJS publishes peer-review articles in Mathematics, Computer Sci

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As Lab-on-Chip platforms with micro-and nano-dimensions evolve biosensors using miniaturized and high-sensitivity cantilevers are becoming more attractive. Although these sensors function in non-isothermal situations, computational mathematics generally ignores the temperature. Conversely, biosensor cannot be designed with a single-layered cantilever. Yet, in Nano-Electro- Mechanical-Systems, the influence of temperature is more likely to be dominant since the surfaceto- volume ratio is higher. In the context of this conclusion, the mathematical modelling comprises temperature and the associated material attributes. This work presents a simple and direct analytical technique for analysing the control of bimetallic cantilevers with NEMS-based sensing and actuation mechanisms. Methodological techniques were used to develop and solve some wellknown models of mathematical equations. Parametric analysis data is a major factor in the functioning of all of the other works studied. The findings of FEA comparisons and experiments reveal that the mathematical model's predictions are more than 20% correct.

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Design of capacitive pressure sensor for continuous glucose monitoring system

Lakshmi,

Rao

2024

Microsyst Technol

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Design of MEMS sensor for the detection of cholera and diarrehea by capacitance modulation

Cited by 7 publications

References 20 publications

Development of a MEMS-Based Biosensor for Analyzing the Bio-Electrical Characteristics of Colon Cancer Cells

Development of a MEMS-Based Biosensor for Analyzing the Bio-Electrical Characteristics of Colon Cancer Cells

Mathematical Modelling and Analysis of Temperature Effects in NEMS Based Bi-Metallic Cantilever for Molecular Biosensing Applications

Design of capacitive pressure sensor for continuous glucose monitoring system

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