Design of measurement strategies for workplace exposures

Kromhout, Hans

doi:10.1136/oem.59.5.349

Cited by 63 publications

(52 citation statements)

References 37 publications

(21 reference statements)

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“…For FA occupational exposure, ceiling concentrations might be a better strategy to evaluate exposure and to develop risk assessment once very high exposures over short periods are missed by TWA 8 h method and, in fact, they are important to know the real risk for health [23,31]. Therefore, as in other investigations [33,34], it is possible to conclude that when measuring only TWA 8 h poor information is obtained, and the method is of less utility to identify processes that should be targeted for controls.…”

Section: Discussionmentioning

confidence: 99%

Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production

Viegas¹,

Ladeira²,

Nunes³

et al. 2010

Toxicology Letters

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Background: According to the Report on Carcinogens, formaldehyde ranks 25 th in the overall U.S. chemical production, with more than 5 million tons produced each year. Given its economic importance and widespread use, many people are exposed to formaldehyde environmentally and/or occupationally. Presently, the International Agency for Research on Cancer classifies formaldehyde as carcinogenic to humans (Group 1), based on sufficient evidence in humans and in experimental animals. Manyfold in vitro studies clearly indicated that formaldehyde can induce genotoxic effects in proliferating cultured mammalian cells. Furthermore, some in vivo studies have found changes in epithelial cells and in peripheral blood lymphocytes related to formaldehyde exposure.

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Section: Discussionmentioning

confidence: 99%

Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production

Viegas¹,

Ladeira²,

Nunes³

et al. 2010

Toxicology Letters

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“…Recognition of the personal, temporal, and spatial variability in exposure concentrations is imperative for the design of efficient and effective sampling strategies, for the interpretation of existing exposure data, and for assigning exposure estimates in an epidemiologic survey (52). The distribution of exposure over the body (ie, spatial variability) has been studied extensively, at least in the relative sense.…”

Section: Exposurementioning

confidence: 99%

Dermal exposure assessment in occupational epidemiologic research

Vermeulen¹,

Stewart²,

Kromhout³

2002

Scand J Work Environ Health

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“…The fact that the DNA was amplified at quite high quantitation cycles wise to assume the most critical contamination scenario (25).…”

Section: Fungal Detection Using Pcrmentioning

confidence: 99%

Assessment of exposure to the Penicillium glabrum complex in cork industry using complementing methods / Ocjena izloženosti kompleksu Penicillium glabrum u proizvodnji pluta s pomoću komplementarnih metoda

Viegas

Sabino

Botelho

et al. 2015

Archives of Industrial Hygiene and Toxicology

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Cork oak is the second most dominant forest species in Portugal and makes this country the world leader in cork export. Occupational exposure to Chrysonilia sitophila and the Penicillium glabrum complex in cork industry is common, and the latter fungus is associated with suberosis. However, as conventional methods seem to underestimate its presence in occupational environments, the aim of our study was to see whether information obtained by polymerase chain reaction (PCR), a molecular-based method, can complement conventional findings and give a better insight into occupational exposure of cork industry workers. We assessed fungal contamination with the P. glabrum complex in three cork manufacturing plants in the outskirts of Lisbon using both conventional and molecular methods. Conventional culturing failed to detect the fungus at six sampling sites in which PCR did detect it. This confirms our assumption that the use of complementing methods can provide information for a more accurate assessment of occupational exposure to the P. glabrum complex in cork industry.

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Design of measurement strategies for workplace exposures

Cited by 63 publications

References 37 publications

Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production

Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production

Dermal exposure assessment in occupational epidemiologic research

Assessment of exposure to the Penicillium glabrum complex in cork industry using complementing methods / Ocjena izloženosti kompleksu Penicillium glabrum u proizvodnji pluta s pomoću komplementarnih metoda

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