In this paper, we propose the tester apparatus for 48 channel GM Tube sensor. The proposed apparatus can test up to 48 channel GM tube simultaneously to detect the defect and analyze the sensor characteristic. 300-1000V variable high voltage generation circuit is utilized for the apparatus suitable for the sensor characteristic. Thus, the proposed system is useful for various GM Tube sensor characteristic analysis. Multiple sensor testing environment is established for the early detection of the defect and the analysis to reduce the costs for manufacturing and rework. Developed 48 channel GM Tube sensor test is evaluated with certified testing equipment and shows excellent performance with respect to the uncertainty of the sensor test results.