Design of histidine containing peptides for better understanding of their coordination mode toward copper(II) by CD spectroscopy

Jakab, Noémi; Gyurcsik, Béla; Körtvélyesi, Tamás; Vosekalna, Ilze; Jensen, Jan H.; Larsen, Erik

doi:10.1016/j.jinorgbio.2007.05.012

Cited by 42 publications

(44 citation statements)

References 53 publications

(51 reference statements)

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“…Their existence is clearly proved by the appearance of a marked positive CD-band around 545 nm be- tween pH 6 and 8 (Figs. 6 and S3b), as also found for the bis-complexes of Ac-HPHPH-NH 2 [42] and other bis-histamine type complexes [63]. The two observed bis-ligand species, CuHL 2 and CuL 2 , possess nearly identical spectral features (see Figs.…”

Section: Interaction Of Ac-hhphg-nh 2 and Ac-hhphghhphg-nh 2 With Copsupporting

confidence: 72%

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Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

Jancsó

Kolozsi

Gyurcsik

et al. 2009

Journal of Inorganic Biochemistry

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Section: Interaction Of Ac-hhphg-nh 2 and Ac-hhphghhphg-nh 2 With Copsupporting

confidence: 72%

“…Since the copper(II) used in the solutions was a natural mixture of the isotopes, the spectrum of each species was calculated as the sum of spectra containing 63 Cu and 65 Cu in their natural abundances. The copper and ligand coupling constants are given in units of Gauss (G; 1 G = 10 -4 T).…”

Section: Epr Measurementsmentioning

confidence: 99%

Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

Jancsó

Kolozsi

Gyurcsik

et al. 2009

Journal of Inorganic Biochemistry

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“…A similar 5,5,6 chelate pattern was also suggested for the Cu II complex of the linear H-Gly-Gly-His-OH. 17 No further deprotonation of 2 was detected in potentiometry up to pH 11. In Fig.…”

mentioning

confidence: 94%

Electrocatalytic water oxidation by Cu^II complexes with branched peptides

et al. 2015

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Two mononuclear Cu II complexes with tetrapeptides incorporating a L-2,3-diaminopropionic acid (dap) branching unit are reported to undergo PCET and catalyse water oxidation. C-terminal His extension of dap (L = 2GH) instead of Gly (L = 3G) lowers the pK a for Cu III H À2 L (9.36 vs. 9.98) and improves the TOF at pH 11 (53 vs. 24 s À1 ).Reactions requiring the synchronous transfer of multiple protons and electrons become energetically viable under mild conditions through the catalytic promotion of proton-coupled electron transfer (PCET) mechanisms that help circumventing high-energy intermediates. 1 Splitting water into its elements, which attracts growing attention as a prospective renewable tool to generate H 2 as an energy carrier, 2-4 ranks among reactions where PCET is of critical importance. Water oxidation catalysts (WOCs) can improve the efficiency of the oxidative half-reaction: 2H 2 O -O 2 + 4H + + 4e À , which has long been considered the bottleneck of the water splitting process. Bioinspired, homogeneous WOCs (Fe, 5 Co, 6 Ru, 7 or Ir 8 ), although inherently less robust than heterogeneous catalysts, 9 represent a meaningful source of mechanistic insight into the multiple proton and electron-transfer events associated with O 2 formation. A growing number of studies conclude that PCET helps in stabilising high-valent MQO or M-O intermediates by preventing charge accumulation upon oxidation and, as a consequence these intermediates can complete the O-O bond formation step. 10 Cu has rich oxygen chemistry, 11 yet, homogeneous WOCs involving this metal appeared only recently, when surprisingly robust Cu II complexes with 2,2 0 -bipyridine (bpy, TOF B 100 s À1 at pH 13) 12 and subsequently, with triglycylglycine (GGGG, or H-Gly-Gly-Gly-Gly-OH, TOF = 33 s À1

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“…Amino acid side chains can also contain different donor centers (E). The most important ones include histidine imidazole [34][35][36][37][38][39][40], cysteine sulfhydryl, aspartic carboxylate [41] and tyrosine phenolate [42]. The hydroxylate groups of serine or threonine, the amide carbonyl group of asparagine or the lysine amine side chain are seldom involved in metal coordination.…”

Section: Formation Of Metallopeptides Peptides As Chelating Agents Fmentioning

confidence: 99%

Tetrazole peptides as copper(II) ion chelators

Łodyga-Chruścińska¹

2011

Coordination Chemistry Reviews

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Design of histidine containing peptides for better understanding of their coordination mode toward copper(II) by CD spectroscopy

Cited by 42 publications

References 53 publications

Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

Electrocatalytic water oxidation by Cu^II complexes with branched peptides

Tetrazole peptides as copper(II) ion chelators

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Design of histidine containing peptides for better understanding of their coordination mode toward copper(II) by CD spectroscopy

Cited by 42 publications

References 53 publications

Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

Electrocatalytic water oxidation by CuII complexes with branched peptides

Tetrazole peptides as copper(II) ion chelators

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Electrocatalytic water oxidation by Cu^II complexes with branched peptides