2013
DOI: 10.1007/978-1-4614-6363-4
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Design of Experiments in Nonlinear Models

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Cited by 125 publications
(106 citation statements)
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“…We have not considered in full the characteristics of the estimation problem that is obtained with the optimized measurement allocation during the optimization procedure; for example, if the parameters can be uniquely determined everywhere in the measurement domain and if there are local minima present in the estimation problem. This is related to the concepts of identifiability and estimability and the reader is referred to Pronzato and Pázman (2013) for further information.…”
Section: Discussionmentioning
confidence: 99%
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“…We have not considered in full the characteristics of the estimation problem that is obtained with the optimized measurement allocation during the optimization procedure; for example, if the parameters can be uniquely determined everywhere in the measurement domain and if there are local minima present in the estimation problem. This is related to the concepts of identifiability and estimability and the reader is referred to Pronzato and Pázman (2013) for further information.…”
Section: Discussionmentioning
confidence: 99%
“…If the model V k ðpÞ is linear in p, the D-optimal solution minimizes the volume of the lower bound for the confidence ellipsoid described by M À1 in (12). The volume of the b-confidence ellipsoid is given by Pronzato and Pázman (2013) …”
Section: Performance Metricmentioning
confidence: 99%
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“…We obtain a formula for computing the maximum radius of any RIGM region based on the properties of an equidistant function that the first two authors introduced in [6]. This function also plays a prominent role in the definition of extended intrinsic curvature of a nonlinear model presented in [8]. While closely related to the intrinsic curvature locally, the equidistant function reflects global rather than local properties of a nonlinear model.…”
Section: Introductionmentioning
confidence: 99%
“…The focus of Silvey (1980) and Fedorov and Hackl (1997) is on the mathematical theory; Atkinson, Donev, and Tobias (2007) and Berger and Wong (2009) are more concerned with applications, whereas Goos and Jones (2011) introduce theory and examples via the JMP software. Pronzato and Pázman (2013) present the theory of optimal design for nonlinear models, while Fedorov and Leonov (2014) illustrate their theory with pharmaceutical applications, particularly dose finding.…”
Section: Theorymentioning
confidence: 99%