Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques

Pandey, Lalit M.

doi:10.1080/14789450.2020.1794831

Cited by 42 publications

(30 citation statements)

References 51 publications

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“…In fact, the detection of SARS‐CoV using the piezoelectric immunosensor has been reported, [ 138 ] and implementation of the recently proposed surface chemistry on the quartz crystal surface of the QCM will allow the early detection of SARS‐CoV‐2 (see Figure a,b). [ 139 ] Exploration to implement these engineered surfaces on the MSMC surface is needed (Figure 21c). Both piezoelectric and magnetostrictive materials are also promising candidates for energy‐harvesting from ambient environmental sources to self‐power biosensors for virus detection and communication.…”

Section: Future Outlookmentioning

confidence: 99%

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

et al. 2020

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fever with or without chills, chest tightness, dry cough, and shortness of breath, while developing patchy to diffuse infiltration of the lungs, as shown radiographically in Figure 1. Identifying and monitoring SARS-CoV-2 infection has become crucially important. A recent projection of the transmission dynamics of SARS-CoV-2 [2] showed that longitudinal serological studies are desperately needed to determine the extent and duration of immunity to SARS-CoV-2. Even in the event of apparent elimination, maintenance of SARS-CoV-2 surveillance is still needed because of a possible resurgence of contagion. In the past, notable viruses have emerged suddenly from obscurity or anonymity, provoking concern from the point of view of immunology regarding their sustained epidemic transmission in naive human populations. More than 70% of these infections have been zoonotic, entering either directly from wild animal reservoirs or indirectly via an intermediate domestic animal host. [3] Ebola virus, avian influenza, human immunodeficiency virus (HIV), and SARS are all examples of zoonoses that have emerged from wild animals, presenting an increasingly serious threat to human health and economies worldwide. Figure 2 shows the trend in the number of people infected with SARS-CoV-2. [4] The spread of the severe acute respiratory syndrome coronavirus has changed the lives of people around the world with a huge impact on economies and societies. The development of wearable sensors that can continuously monitor the environment for viruses may become an important research area. Here, the state of the art of research on biosensor materials for virus detection is reviewed. A general description of the principles for virus detection is included, along with a critique of the experimental work dedicated to various virus sensors, and a summary of their detection limitations. The piezoelectric sensors used for the detection of human papilloma, vaccinia, dengue, Ebola, influenza A, human immunodeficiency, and hepatitis B viruses are examined in the first section; then the second part deals with magnetostrictive sensors for the detection of bacterial spores, proteins, and classical swine fever. In addition, progress related to early detection of COVID-19 (coronavirus disease 2019) is discussed in the final section, where remaining challenges in the field are also identified. It is believed that this review will guide material researchers in their future work of developing smart biosensors, which can further improve detection sensitivity in monitoring currently known and future virus threats.

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Section: Future Outlookmentioning

confidence: 99%

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

et al. 2020

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“…For this purpose, SAMs with a varied range of hydrophobicity, which is controlled by surface functional groups, were investigated and developed [103]. The SAMs, which have terminal -COOH and -CH 3 groups, have been shown as the most suitable for the specific and strong binding of SARS-CoV-2 S-protein [104]. The main working principle of the QCM is altering (decreasing) the frequency of the vibrating quartz crystal with the increasing the adsorbed mass [105].…”

Section: Quartz Crystal Microbalance Based Biosensorsmentioning

confidence: 99%

Affinity Sensors for the Diagnosis of COVID-19

et al. 2021

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The coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was proclaimed a global pandemic in March 2020. Reducing the dissemination rate, in particular by tracking the infected people and their contacts, is the main instrument against infection spreading. Therefore, the creation and implementation of fast, reliable and responsive methods suitable for the diagnosis of COVID-19 are required. These needs can be fulfilled using affinity sensors, which differ in applied detection methods and markers that are generating analytical signals. Recently, nucleic acid hybridization, antigen-antibody interaction, and change of reactive oxygen species (ROS) level are mostly used for the generation of analytical signals, which can be accurately measured by electrochemical, optical, surface plasmon resonance, field-effect transistors, and some other methods and transducers. Electrochemical biosensors are the most consistent with the general trend towards, acceleration, and simplification of the bioanalytical process. These biosensors mostly are based on the determination of antigen-antibody interaction and are robust, sensitive, accurate, and sometimes enable label-free detection of an analyte. Along with the specification of biosensors, we also provide a brief overview of generally used testing techniques, and the description of the structure, life cycle and immune host response to SARS-CoV-2, and some deeper details of analytical signal detection principles.

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“… Fetal bovine serum (FBS) COVID-19 RdRp coding sequences Optomagnetic sensing Magnetic nanoparticle (MNP) [ 88 ] Piezoelectric Nano-biosensors 10. Oral swab samples COVID-19 spike protein Quartz crystal microbalance (QCM) Nanoparticles [ 89 ] …”

Section: Biosensors For Covid-19mentioning

confidence: 99%

Critical neurological features of COVID-19: Role of imaging methods and biosensors for effective diagnosis

Singh¹,

Allawadhi²,

Khurana³

et al. 2021

Sensors International

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COVID-19 is a respiratory infection that has been declared as a global health crisis by the WHO. It mainly affects the respiratory system. Apart from respiratory system, it also affects other organs as well including the brain. Numerous emerging reports have demonstrated that the COVID-19 has detrimental effects on neurological functions, and can lead to severe impairment of the nervous system. The neurological manifestations linked with COVID-19 include headache, anosmia, encephalitis, epileptic seizures, Guillain-Barre syndrome, stroke and intracerebral hemorrhage alongwith multiple others complications. The CNS related complications may be severe are they are linked with poor diagnosis which may worsen the condition. Therefore, there is a need to precisely understand the neurological sequelae along with upcoming clinical outcomes. Here, we presented a brief review of neurological complications and symptoms associated with COVID-19 along with brain imaging findings. Further, we have discussed about the emerging biosensing approaches which may aid in rapid, precise and mass diagnosis of COVID-19.

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Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques

Cited by 42 publications

References 51 publications

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

Affinity Sensors for the Diagnosis of COVID-19

Critical neurological features of COVID-19: Role of imaging methods and biosensors for effective diagnosis

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