Design of Biointerfaces Using Informatics : From Monolayers to Polymer Surfaces

Abstract

In this review, we summarize the current situation of materials informatics in the field of biomaterials. Different from other fields working on solid state materials, the functions of biomaterials are difficult to predict by using theoretical or computational approaches. Therefore, we need to collect data experimentally for the construction of dataset. We introduce our recent achievements on the prediction of protein adsorption onto self-assembled monolayers (SAMs) and polymer blush films. In addition, we describe the procedure of the data acquisition, selection of descriptors and algorithms.