Design of an observational multi-country cohort study to assess immunogenicity of multiple vaccine platforms (InVITE)

Sereti, Irini; Shaw‐Saliba, Kathryn; Dodd, Lori E.; Dewar, Robin; Laverdure, Sylvain; Brown, Shawn T.; Mbaya, Olivier Tshiani; Tamfum, Jean Jacques Muyembe; Mblala-Kingebeni, Placide; Sow, Ydrissa; Akpa, Esther; Haidara, Mory Cherif; Tchos, Karine Fouth; Béavogui, Abdoul Habib; Neal, Aaron; Arlinda, Dona; Lokida, Dewi; Grue, Louis; Smolskis, Mary; McNay, Laura A.; Gayedyu-Dennis, Dehkontee; Ruíz-Palacios, Guillermo M.; Montenegro-Liendo, Abelardo; Tounkara, Moctar; Samake, Seydou; Jargalsaikhan, Ganbolor; Zulkhuu, Delgersaikhan; Weyers, Shera; Bonnett, Tyler; Potter, Gail E.; Stevens, Randy; Rupert, Adam; Aboulhab, Jamila; Biampata, Jean-Luc; Delamo, Alexandre; Camara, Bienvenu Salim; Indonesia, Herman Kosasih; Karyana, Muhammad; Duworko, J. Tanu; Regalado‐Pineda, Justino; Guerra-de-Blas, Paola Del Carmen; Doumbia, Seydou; Dabitao, Djeneba; Dashdorj, Naranjargal J.; Dashdorj, Naranbaatar; Newell, Kevin; Francis, Alyson; Rubenstein, Kevin; Bera, Victoria; Gulati, Iman; Sardana, Ratna; Millard, Monica; Ridzon, Renée; Hunsberger, Sally

doi:10.1371/journal.pone.0273914

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…LaRed has also simultaneously collaborated with other networks across different continents. The group of six networks, alongside the ONUM (Sanskrit for spreading knowledge) Foundation in Mongolia, is conducting an observational cohort study of COVID-19 vaccine immunogenicity and allows the comparison of responses to different vaccines in different environments [ 13 ].…”

Section: International Clinical Research Network – a Collaborative Ap...mentioning

confidence: 99%

International clinical research networks – a collaborative approach for pandemic preparedness and response: The case of The Mexican Emerging Infectious Disease Clinical Research Network (LaRed)

et al. 2023

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Section: International Clinical Research Network – a Collaborative Ap...mentioning

confidence: 99%

International clinical research networks – a collaborative approach for pandemic preparedness and response: The case of The Mexican Emerging Infectious Disease Clinical Research Network (LaRed)

et al. 2023

Self Cite

View full text Add to dashboard Cite

SARS-CoV-2 seroprevalence in vaccine-naïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali

Laverdure,

Kazadi,

Kone

et al. 2024

International Journal of Infectious Diseases

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Challenges of conducting an international observational study to assess immunogenicity of multiple COVID-19 vaccines

Sardana,

Kingebeni,

Snc

et al. 2023

PLOS Glob Public Health

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The International Study on COVID-19 Vaccines to Assess Immunogenicity, Reactogenicity, and Efficacy is an observational study to assess the immunogenicity of COVID-19 vaccines used in Democratic Republic of Congo, Guinea, Indonesia, Liberia, Mali, Mexico, and Mongolia. The study, which has enrolled 5,401 adults, is prospectively following participants for approximately two years. This study is important as it has enrolled participants from resource-limited settings that have largely been excluded from COVID-19 research studies during the pandemic. There are significant challenges to mounting a study during an international health emergency, especially in resource-limited settings. Here we focus on challenges and hurdles encountered during the planning and implementation of the study with regard to study logistics, national vaccine policies, pandemic-induced and supply chain constraints, and cultural beliefs. We also highlight the successful mitigation of these challenges through the team’s proactive thinking, collaborative approach, and innovative solutions. This study serves as an example of how established programs in resource-limited settings can be leveraged to contribute to biomedical research during a pandemic response. Lessons learned from this study can be applied to other studies mounted to respond rapidly during a global health crisis and will contribute to capacity for stronger pandemic preparedness in the future when there is a crucial need for urgent response and data collection.

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Design of an observational multi-country cohort study to assess immunogenicity of multiple vaccine platforms (InVITE)

Cited by 3 publications

References 12 publications

International clinical research networks – a collaborative approach for pandemic preparedness and response: The case of The Mexican Emerging Infectious Disease Clinical Research Network (LaRed)

International clinical research networks – a collaborative approach for pandemic preparedness and response: The case of The Mexican Emerging Infectious Disease Clinical Research Network (LaRed)

SARS-CoV-2 seroprevalence in vaccine-naïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali

Challenges of conducting an international observational study to assess immunogenicity of multiple COVID-19 vaccines

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