Design of aggregation-induced emission-active fluorogen-based nanoparticles for imaging and scavenging Alzheimer's β-amyloid by photo-oxygenation

Abstract

Novel photo-oxidant nanoparticles (T-LD NPs) showed effective near-infrared fluorescence imaging of β amyloid (Aβ), and potent inhibition of Aβ fibrillation and fast disaggregation of mature Aβ fibrils by photo-oxygenation under laser irradiation.