Design of a Zn-MOF biosensor via a ligand “lock” for the recognition and distinction of S-containing amino acids

Abstract

A new method of introducing a ‘lock’ ligand into the frame of MOFs is described to achieve the first example of a MOF-based biosensor for the recognition and distinction of S-containing amino acids.

Water-Stable 1D Double-Chain Cu Metal–Organic Framework-based Electrochemical Biosensor for Detecting l-Tyrosine

“…The scan rate influences for l -Tyr are shown in Figures S7 and S8. All the peak current densities toward ν 1/2 exhibited a nearly linear variation, which suggests a mass-transfer process . All the values were calculated according to the methods from previous reports …”

“…All the peak current densities toward ν 1/2 exhibited a nearly linear variation, which suggests a masstransfer process. 40 All the values were calculated according to the methods from previous reports. 41 Differential Pulse Voltammetry Behavior Studies.…”

Conductive Metal‐Organic Frameworks: Electronic Structure and Electrochemical Applications

“…reported the electroanalytical behaviour of an as‐synthesized Cu‐MOF ‐ modified CPE via electro‐reduction of H 2 O 2 at physiological pH and electro‐oxidation of glucose in alkaline medium [247a] . The as‐obtained Zn‐MOF – modified Au electrode (AuE) was used as an electrochemical biosensor for recognizing and distinguishing S‐containing amino acids like L‐cysteine, L‐methionine and L‐cystine with excellent electrochemical activity [247c–d] . Certain conductive 2D MOFs drop‐casted on GCE and then covered by ion‐selective membrane were proved to form a potential electrochemical sensor for cations and anions and capable of long‐term analysis without deterioration in performance.…”

Fast Synthesis of Hybrid Zeolitic Imidazolate Frameworks (HZIFs) with Exceptional Acid–Base Stability from ZIF-8 Precursors

“…Porous coordination polymers (PCPs) or metal–organic frameworks (MOFs) are a new class of crystalline porous materials consisting of metal ions or clusters coordinated by organic ligands. − MOFs have received extensive attention not only for their fascinating structure features but also for their potential applications in gas adsorption/separation, catalysis, and so on. − Despite numerous advantages, applications of many MOFs are ultimately limited by their stability under harsh conditions. Hence, design and synthesis of stable MOF architectures have become one of the most active research fields. − Considering the intrinsic stability of MOFs, stable MOFs can be classified into two categories: high-valent metal–carboxylate frameworks and low-valent metal–imidazolate frameworks, represented by MILs (Materials Institute Lavoisier) and zeolitic imidazolate frameworks (ZIFs) series, respectively. − ZIFs have gained wide attention due to their high thermal/chemical stability, easy crystallization, and cheap prices of reactants as well as the high surface area and porosity. , Many efforts have been devoted to developing novel approaches (i.e., microwave, mechanochemical, and flow chemistry synthesis for large scale syntheses) …”