Design of a Small Centrifugal Blood Pump With Magnetic Bearings

Jahanmir, Said; Hunsberger, Andrew; Ren, Zhengru; Heshmat, Hooshang; Heshmat, Crystal A.; Tomaszewski, Michael J.; Walton, James F.

doi:10.1111/j.1525-1594.2009.00883.x

Cited by 7 publications

(5 citation statements)

References 37 publications

(41 reference statements)

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“…The appearances in contact with blood may get a special coating of titanium microspheres that permanently bond to the surface. With this layer, blood cells adhere to the surface [46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61]. A particular type of polyurethane polymer has been used as a surface coating to provide blood cell adherence [46,48,57] whereas polyester is often employed in other parts of the system such as tubular grafts [57,62,63].…”

Section: Design and Materials Of Blood Pumpsmentioning

confidence: 99%

Biocompatible materials of pulsatile and rotary blood pumps: A brief review

Ahmed

Wang

Yang

2020

Reviews on Advanced Materials Science

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The biomedical materials that have been used in the structure of heart pumps are classified as biocompatible, and these can be metals, polymers, ceramics, and composites. Their positions in the pump vary according to the part’s function. Whereas various materials have different properties, all biomaterials chosen for cardiovascular applications should have excellent blood biocompatibility to reduce the likelihood of hemolysis and thrombosis. There are two major categories of the heart pumps; pulsatile and rotary blood pumps (axial and centrifugal) and the features of some of these materials allow them to be used in both. Rotary and pulsatile blood pump devices have to be fabricated from materials that do not result in adverse biological responses. The purpose of this review is to study the available biocompatible materials for the pulsatile and rotary blood pumps as clinically-approved materials and prototype heart pump materials. The current state of bio-compatible materials of rotary and pulsatile blood pump construction is presented. Some recent applications of surface amendment technology on the materials for heart assist devices were also reviewed for better understanding. The limitations of heart assist devices, and the future direction of artificial heart elements have been considered. This review will be considered as a comprehensive reference to rapidly understanding the necessary research in the field of biocompatible materials of pulsatile and blood rotary pumps.

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Section: Design and Materials Of Blood Pumpsmentioning

confidence: 99%

Biocompatible materials of pulsatile and rotary blood pumps: A brief review

Ahmed

Wang

Yang

2020

Reviews on Advanced Materials Science

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“…The Windkessel model is analogous to an electrical circuit, with pressure representing electrical potential and flow representing current (Hales 1733; Frank 1899). One major use of mock loops is to study cardiac assist devices, such as axial flow pumps (Camus et al 2007;Nakatani et al 1994), centrifugal pumps (Jahanmir et al 2009;Takami 2006) and counterpulsators (Bowles et al 1991;Kolyva et al 2010;Papaioannou et al 2004). They are also useful to study heart valves (Scharfscherdt et al 2009) in the aortic (Kuehnel et al 2005), mitral (Jimenez et al 2005) and pulmonary (Gohean et al 2006) positions, as well as being used as ''bioreactors'' for bioengineering tissue valves (Bowles et al 2010;Dumont et al 2002).…”

Section: In Vitro Modelingmentioning

confidence: 99%

Cardiovascular Modeling

Biglino¹,

Schievano²,

Muthurangu³

et al. 2011

Clinical Cardiac MRI

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“…Said Jahanmir et al. (44) of MiTiHeart Corp., Gaithersburg, MD, USA reported on their blood pump design with a magnetically levitated rotor. Based on the estimated operating speed and clearance between the rotor and stator, the motor characteristics and dimensions were estimated.…”

Section: Cardiac Support and Blood Pumpsmentioning

confidence: 99%

Artificial Organs 2009: A Year in Review

Malchesky¹

2010

Artificial Organs

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In this editor's review, all articles published in 2009 are organized by category and briefly summarized. As Artificial Organs continues in the original mission of its founders "to foster communications in the field of artificial organs on an international level," we strive to publish the very best developments and clinical applications of artificial organ technologies in this broad and expanding field. In this editor's review, we aim to provide a reflection of the currently available worldwide knowledge that is intended to advance and improve human life while providing insight for continued application of technologies and methods of organ replacement, recovery, and regeneration. APHERESISClaudia Stefanutti et al. (1) of the University of Rome, Rome, Italy studied lowering lipoprotein Lp(a) using a reusable low density lipoprotein (LDL)-adsorber that allowed the removal of both LDL and Lp(a) from plasma. Two male patients with hyper-Lp(a) lipoproteinemia, without elevation of LDL-cholesterol, who had not responded to diet and medication were submitted to 50 LDL Lp(a) aphereses at weekly and biweekly intervals. Total cholesterol, LDL cholesterol, triglycerides, and Lp(a) plasma levels fell significantly. High density lipoprotein (HDL) cholesterol concentrations in plasma did not show a statistically significant change. Clinically, all sessions were well tolerated and no undesired reactions were reported. The adsorber's reusability for several sessions was confirmed.Claudia Stefanutti et al.(2) also reported on a multicenter study of therapeutic exchange (TPE) in patients with severe hypertriglyceridemia (sHTG). Seventeen patients who had not responded to conventional medical therapy (fat-free diet plus pharmaceutical interventions) were referred for TPE. Two hundred and seventeen TPE sessions were performed, and therapy is ongoing for 29.4% of the patients. After treatment, the mean plasma TG and total cholesterol concentrations were significantly reduced. The removal of triglyceride-richlipoproteins prevented relapses of acute pancreatitis. TPE provides a therapeutic option for preventing life-threatening sHTG. BLOOD SUBSTITUTESSabura Neya et al.(3) of Chiba University, Inage-Yayoi, Chiba, Japan evaluated the biological function of the core modified porphyrin isomers such as porphycene, corrphycene, and hemiporphycene. The iron complexes stoichiometrically coupled with apomyoglobin afford stable holoproteins. The oxygen affinity of the reconstituted myoglobins (Mb) changed over a 60 000-fold range depending on the

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Design of a Small Centrifugal Blood Pump With Magnetic Bearings

Cited by 7 publications

References 37 publications

Biocompatible materials of pulsatile and rotary blood pumps: A brief review

Biocompatible materials of pulsatile and rotary blood pumps: A brief review

Cardiovascular Modeling

Artificial Organs 2009: A Year in Review

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