Design of a simple ultrasound/CT fusion image fusion solution for the evaluation of prostate seed brachytherapy

Abstract

Ahtract-The purpose of this project is to devise a solutios~ that will enable physicians, medical physicists and dosimetrists to quantitatively evaluate the success of prostate brachytherapy procedures. It is proposed that a simple ultrasoundfl image fusion solution can be developed and implemented to imprwe the current post-surgical evaluation process.

Medical image fusion: A survey of the state of the art

“…There are several application areas where CT images are considered the prime modality. some of these major applications are the following: (1) head and neck cancer diagnosis [219,192,220,221,222,199], (2) cancer treatment [51,223], (3) image segmentation and integration [51,216], (4) lung cancer treatment [224,225,182,226,227,228,229,230,231,232], (5) prostate cancer treatment [148,233,234,150,235,151,154,155,156,236,237,157,158,238,159,239,160,216,128,240,164,241,165,167,168,242,133], (6) 3D conformal radiation therapy…”

“…There is a wide range of applications where the ultrasound images are used to infer medical data. Some of these are for prostate cancer treatment [271,149,278,234,279,237,162,164,241,170], conformal radiation therapy [271], brachytherapy prostate implant [264,278,234,237,164], image fusion [279,61,162], breast cancer detection [280], liver tumor diagnosis [258], prostate biopsy [177], and esophageal cancer diagnosis [260].…”

“…These major deficiencies necessitate the need to use other modalities to ensure the accuracy of imaging and localization of the regions under test for diagnostic measurements. Examples of fusion techniques that incorporate ultrasound in it are ultrasound-X-rays [271], ultrasound-CT [264,234,237,164,241,258], ultrasound-uoroscopic [278], nuclear medicine-ultrasound [204], microscopy-ultrasound [37], ultrasound-CAD-mammogramsinfrared [280], ultrasound-MRI [149,162,170,177] and PET-CT-ultrasound [260].…”

“…Prostate is another organ that has been studied using multi-modal medical images. There exists a range of techniques and studies on prostrate based image fusion, that often face the challenge deformation of prostrate in multi-modal imaging setups [271,148,149,174,264,278,234,279,282,150,151,152,311,155,312,156,236,237,215,159,239,160,313,162,163,241,165,168,169,171]. The medical image analysis techniques on prostate include localization of the prostate for 3D conformal radiation therapy [148], prostate localization in the post-planning setting [314] evaluation of prostate gland motion and volume changes [315], evaluation of prostate seed brachytherapy [234], thermal ablation of the prostate cancer [152,153], histology study of prostate tissue [279], post implant dosimetric analysis of prostate brachytherapy [157,161], prostate brachytherapy [237,157,161], and biomechanical modeling of prost...…”

“…The medical image analysis techniques on prostate include localization of the prostate for 3D conformal radiation therapy [148], prostate localization in the post-planning setting [314] evaluation of prostate gland motion and volume changes [315], evaluation of prostate seed brachytherapy [234], thermal ablation of the prostate cancer [152,153], histology study of prostate tissue [279], post implant dosimetric analysis of prostate brachytherapy [157,161], prostate brachytherapy [237,157,161], and biomechanical modeling of prostate motion [316]. The imaging modalities that deal with prostate include ultrasound [271,149,264,278,234,279,237,162,241,316], X-rays [271], CT [148,174,264,234,150,154,239,155,156,236,237,157,160,313,161,241,165,168], MRI [148,…”