Design of a label-free photonic crystal refractive index sensor for biomedical applications

Danaie, Mohammad; Kiani, Behnam

doi:10.1016/j.photonics.2018.06.004

Cited by 124 publications

(35 citation statements)

References 49 publications

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“…Additionally, the coupling strength also depends on the modulation amplitude. A deeper modulation thus leads to longitudinal shortening of the optimized sensor, but can also increase extrinsic waveguide loss with thinner waveguide widths or widen the resonance spectral pattern as described in equation (5). In Fig.…”

Section: B Coupled-local-mode Theory Approachmentioning

confidence: 99%

“…Integrated optical chemical sensors can detect and measure the concentration of an analyte by accessing a particular optical parameter. Various designs for integrated refractometric measurements have been proposed over the years, including integrated interferometers [2], ring resonators [3], plasmonics [4], photonic crystals [5] and gratings [6]. These are principally reagent-mediated sensors [7], implying that they monitor the optical response of an intermediate species (typically a solid porous matrix) whose optical properties depend on the presence of the target gaseous analyte.…”

Section: Introductionmentioning

confidence: 99%

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Integrated Width-Modulated SiN Long Period Grating Designed for Refractometric Applications

Deleau

Seat

Surre

et al. 2021

J. Lightwave Technol.

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A novel integrated photonic structure based on Long Period Waveguide Gratings (LPWGs) relying on channel-width modulation is proposed and tested for refractometric applications. These LPWGs have been fabricated through a Silicon Nitride process and experimentally characterized in terms of both surface and bulk sensitivities. Surface sensing configuration is first achieved by propagating one of the coupling optical modes into an epoxy-based negative photoresist SU8 cladding region that is in contact with the analyte via its outer surface. We subsequently show that the proposed LPWGs cladding layer can be advantageously replaced by a gas-porous polymeric bulk layer such as Styrene-co-AcryloNitrile (SAN) as the cladding region to be directly sensed to anticipate future gas sensing applications. Here, bulk sensing is optimized by increasing the analyte's influence on the modal propagation constants as it is demonstrated to be currently the most promising solution to effectively enhance the figure of merit of long period gratings of given lengths. Using varying water-glycerol mixtures, the surface sensitivity of these LPWGs has been measured at up to 240 nm per RI unit (RIU) that is in agreement with simulation. In addition, the bulk sensitivity has been indirectly estimated to be ⇠1900 nm/RIU via temperature measurements, which corroborates simulation results, thereby paving the way towards gas sensing applications.Index Terms-Integrated photonics, long period grating, refractometry, coupled-local-mode theory, silicon photonics.

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Section: B Coupled-local-mode Theory Approachmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Integrated Width-Modulated SiN Long Period Grating Designed for Refractometric Applications

Deleau

Seat

Surre

et al. 2021

J. Lightwave Technol.

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“…SPPs are nowadays used to design optical devices on sub-wavelength scale due to overcoming the diffraction limit [1][2][3]. Accordingly, plasmonic devices based on SPPs can occupy many less area than other optical techniques such as photonic crystal devices [4][5][6]. Among the nanostructures that have been proposed for guiding SPPs efficiently, the metalinsulator-metal (MIM) waveguides are the most desirable.…”

Section: Introductionmentioning

confidence: 99%

Tunable single‐mode bandpass filter based on metal–insulator–metal plasmonic coupled U‐shaped cavities

Khani

Danaie

Rezaei

2019

IET Optoelectronics

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“…Due to the inherent effective refractive index of the optical fiber, higher-order cladding modes with a lower effective refractive index in these sensing structures, which are required for sensing a low concentration of aqueous solution, and even gas, is difficult to excite. In some RI sensing applications, especially biosensors, there is an increasing need to detect the resolution of the low concentration solution, such as in the medical community and for biomedical sensing measurement [6,7,8,9,10]. Therefore, it is desirable to improve the RI sensing sensitivity of a low concentration solution, and even the gas, with a lower refractive index.…”

Section: Introductionmentioning

confidence: 99%

In-Fiber Closed Cavity Interferometric High-Resolution Aqueous Solution and Alcohol Gas Refractometer

Liu

et al. 2019

Sensors

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An optical fiber interferometric refractometer for alcohol gas concentration and low refractive index (RI) solution (with 1.33–1.38 RI range) measurement is theoretically and experimentally demonstrated. The refractometer is based on a single-mode thin-core single-mode (STS) interferometric structure. By embedding a suitably sized air cavity at the splicing point, high-order cladding modes are successfully excited, which makes the sensor more suitable for low RI solution measurement. The effect of the air cavity’s diameter on the sensitivity of alcohol gas concentration was analyzed experimentally, which proved that RI sensitivity will increase with an enlarged diameter of the air cavity. On this basis, the air cavity is filled with graphene in order to improve the sensitivity of the sensor; and the measured sensitivity of the alcohol gas concentration is −1206.1 pm/%. Finally, the characteristics of the single-cavity structure, graphene-filled structure and double-cavity structure sensors are demonstrated, and the linear RI sensitivities are −54.593 nm/RIU (refractive index unit), −85.561 nm/RIU and 359.77 nm/RIU, respectively. Moreover, these sensor structures have the advantages of being compact and easily prepared.

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Design of a label-free photonic crystal refractive index sensor for biomedical applications

Cited by 124 publications

References 49 publications

Integrated Width-Modulated SiN Long Period Grating Designed for Refractometric Applications

Integrated Width-Modulated SiN Long Period Grating Designed for Refractometric Applications

Tunable single‐mode bandpass filter based on metal–insulator–metal plasmonic coupled U‐shaped cavities

In-Fiber Closed Cavity Interferometric High-Resolution Aqueous Solution and Alcohol Gas Refractometer

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