Photonic-plasmonic hybrid microcavities, which possess a higher figure of merit Q/V (the ratio of quality factor to mode volume) than that of pure photonic microcavities or pure plasmonic nano-antennas, play key roles in enhancing light–matter interaction. In this review, we summarize the typical photonic-plasmonic hybrid microcavities, such as photonic crystal microcavities combined with plasmonic nano-antenna, whispering gallery mode microcavities combined with plasmonic nano-antenna, and Fabry–Perot microcavities with plasmonic nano-antenna. The physics and applications of each hybrid photonic-plasmonic system are illustrated. The recent developments of topological photonic crystal microcavities and topological hybrid nano-cavities are also introduced, which demonstrates that topological microcavities can provide a robust platform for the realization of nanophotonic devices. This review can bring comprehensive physical insights of the hybrid system, and reveal that the hybrid system is a good platform for realizing strong light–matter interaction.