Abstract:A series of sixteen substituted pyrazole oxadiazole derivatives are designed, synthesised and characterized by 1H NMR, 13C NMR and mass spectrometry. The ligands have been docked with Acetylcholine receptor to understand the binding efficiency and amino acids interactions, indicative of all of the sixteen molecules bind efficiently better than Fipronil and Pyrafluprole. These compounds will provide a lead for designing new compounds with improved insecticidal activity.
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