Design and Synthesis of Some Substituted Acridine Derivatives of Anticipated Antitumor Activity

Abstract

consists of phenylhydrazinocarbonylmethyl 9-(4-substituted phenyl)aminoacridine-4-carboxylate 12a-k, while the third series comprises 4-substituted phenylcarbamoylmethyl 9-(4-substituted phenyl)aminoacridine-4-carboxylate 15a-k. The fourth one belongs to phenylcarbamoylmethyl 9-(4-substituted phenyl)aminoacridine-4-carboxylate 17a-j. The chemical structure of synthesized compounds was elucidated by spectral data and elemental analysis. Seventeen selected compounds (