Abstract:Provoked by multifarious applicability of nitrogen heterocycles and hypervalent silicon analogues in drug designing, we attempted the synthesis and structural characterization of a family of heterocyclic appended Organosilatranes tethered with an azomethine linkage by employing a three‐step preparation route and carried out introspection into their prospective bioactivities. Using MOLINSPIRATION and ADMET toolkits, pharmacokinetic profiles of the designed scaffolds were investigated and the results showed thei… Show more
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