Design and synthesis of gold nanostars-based SERS nanotags for bioimaging applications

Andreiuk, Bohdan; Nicolson, Fay; Clark, Louise; Panikkanvalappil, Sajanlal R.; Kenry, Kenry; Rashidian, Mohammad; Harmsen, Stefan; Kircher, Moritz F.

doi:10.7150/ntno.61244

Cited by 38 publications

(28 citation statements)

References 204 publications

(292 reference statements)

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“…The reducing, capping, and shape‐directing agents and reaction conditions (temperature, solvent, mixing speed, and pH) affect outcomes and the reproducibility of published synthetic protocols. [ 29 ] Therefore, the ongoing focus is the development of reproducible preparation methods to obtain nanoparticles with pristine surfaces and structural homogeneity.…”

Section: Nanostructured Plasmonic Metals: Effect Of Tipsmentioning

confidence: 99%

New Trends in Nanoarchitectured SERS Substrates: Nanospaces, 2D Materials, and Organic Heterostructures

Guselnikova

Lim

Kim

et al. 2022

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105

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This article reviews recent fabrication methods for surface‐enhanced Raman spectroscopy (SERS) substrates with a focus on advanced nanoarchitecture based on noble metals with special nanospaces (round tips, gaps, and porous spaces), nanolayered 2D materials, including hybridization with metallic nanostructures (NSs), and the contemporary repertoire of nanoarchitecturing with organic molecules. The use of SERS for multidisciplinary applications has been extensively investigated because the considerably enhanced signal intensity enables the detection of a very small number of molecules with molecular fingerprints. Nanoarchitecture strategies for the design of new NSs play a vital role in developing SERS substrates. In this review, recent achievements with respect to the special morphology of metallic NSs are discussed, and future directions are outlined for the development of available NSs with reproducible preparation and well‐controlled nanoarchitecture. Nanolayered 2D materials are proposed for SERS applications as an alternative to the noble metals. The modern solutions to existing limitations for their applications are described together with the state‐of‐the‐art in bio/environmental SERS sensing using 2D materials‐based composites. To complement the existing toolbox of plasmonic inorganic NSs, hybridization with organic molecules is proposed to improve the stability of NSs and selectivity of SERS sensing by hybridizing with small or large organic molecules.

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Section: Nanostructured Plasmonic Metals: Effect Of Tipsmentioning

confidence: 99%

New Trends in Nanoarchitectured SERS Substrates: Nanospaces, 2D Materials, and Organic Heterostructures

Guselnikova

Lim

Kim

et al. 2022

Small

105

View full text Add to dashboard Cite

show abstract

“…In this case, two seed‐mediated synthetic approaches were tested: (i) a surfactant‐free method in water using HAuCl 4 , AgNO 3 , HCl, AA, and the seeds, and (ii) a PVP based approach in DMF using PVP, HAuCl 4 , and seeds [54] . According to the study, the droplet microfluidic platform provides higher quality Au NSts due to the better mixing of the reagents in the drops [55] …”

Section: Synthesis Of Au Nanostarsmentioning

confidence: 99%

Gold Nanostars: Synthesis, Optical and SERS Analytical Properties

et al. 2022

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Gold nanostars are among the most efficient plasmonic nanomaterials for optical sensing with surface enhanced Raman scattering. In recent years, gold nanostars have increased relevance in physics, analytical chemistry, environmental science, biology and medicine, and in particular in sensing and therapy. These colloids can sustain ultrastrong electromagnetic fields which allow their use as single particles optical enhancers; are colloidally stable and may have a marked catalytical activity. Due to their exotic shape, these colloids present characteristic optical and reactive behaviors. Here, we briefly discuss the optical properties, the synthetic routes and the analytical applications of these nanoparticles.

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“…Biopsy and radiography are not sensitive enough to identify melanoma in its early stages. In recent years, several attempts have been made to develop effective theranostics modalities that combine diagnostic and therapeutic roles to enhance cancer treatment ( Andreiuk et al, 2022 ). Surface-enhanced Raman spectroscopy (SERS) is gaining popularity in the bioimaging and diagnostic fields.…”

Section: Functionalized Nanomaterials For Skin Cancer Theranosticsmentioning

confidence: 99%

Functionalization of Nanomaterials for Skin Cancer Theranostics

Zhang

Zhu

Hou

et al. 2022

Front. Bioeng. Biotechnol.

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Skin cancer has drawn attention for the increasing incident rates and high morbidity worldwide. Timely diagnosis and efficient treatment are of paramount importance for prompt and effective therapy. Thus, the development of novel skin cancer diagnosis and treatment strategies is of great significance for both fundamental research and clinical practice. Recently, the emerging field of nanotechnology has profoundly impact on early diagnosis and better treatment planning of skin cancer. In this review, we will discuss the current encouraging advances in functional nanomaterials for skin cancer theranostics. Challenges in the field and safety concerns of nanomaterials will also be discussed.

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Design and synthesis of gold nanostars-based SERS nanotags for bioimaging applications

Cited by 38 publications

References 204 publications

New Trends in Nanoarchitectured SERS Substrates: Nanospaces, 2D Materials, and Organic Heterostructures

New Trends in Nanoarchitectured SERS Substrates: Nanospaces, 2D Materials, and Organic Heterostructures

Gold Nanostars: Synthesis, Optical and SERS Analytical Properties

Functionalization of Nanomaterials for Skin Cancer Theranostics

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