Design and synthesis of a new series of amphiphilic peptide-β-cyclodextrins as phase transfer carriers for glucosamine

Seyedi, Seyed Mohammad; Sadeghian, Hamid; Jabbari, Atena; Assadi, A.; Momeni, Hamideh

doi:10.1016/j.tet.2010.06.075

Cited by 11 publications

(6 citation statements)

References 20 publications

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“…11 The desired structures have been synthesized as esters of the six primary hydroyl groups of a-CD and the carboxyl moiety of N-acetylated amino acids: leucine (Leu), valine (Val), phenylalanine (Phe), methionine (Met) and tryptophan (Trp) (Scheme 1).…”

Section: Resultsmentioning

confidence: 99%

Synthesis of new series of α-cyclodextrin esters as dopamine carrier molecule

Seyedi

Sadeghian

Jabbari

et al. 2011

Bioorganic & Medicinal Chemistry

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Section: Resultsmentioning

confidence: 99%

Synthesis of new series of α-cyclodextrin esters as dopamine carrier molecule

Seyedi

Sadeghian

Jabbari

et al. 2011

Bioorganic & Medicinal Chemistry

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“…Table 3 presents valuable examples of recently reported applications of organized amphiphilic cyclodextrin assemblies [ 28 , 30 , 35 , 36 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 ]. For a broader range of potential applications of cyclodextrin-based nanomaterials, the reader is advised to consult previous publications [ 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 ].…”

Section: Potential Application Of Supramolecular Assemblies Of Ampmentioning

confidence: 99%

Nano-Assemblies of Modified Cyclodextrins and Their Complexes with Guest Molecules: Incorporation in Nanostructured Membranes and Amphiphile Nanoarchitectonics Design

2014

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A variety of cyclodextrin-based molecular structures, with substitutions of either primary or secondary faces of the natural oligosaccharide macrocycles of α-, β-, or γ-cyclodextrins, have been designed towards innovative applications of self-assembled cyclodextrin nanomaterials. Amphiphilic cyclodextrins have been obtained by chemical or enzymatic modifications of their macrocycles using phospholipidyl, peptidolipidyl, cholesteryl, and oligo(ethylene oxide) anchors as well as variable numbers of grafted hydrophobic hydrocarbon or fluorinated chains. These novel compounds may self-assemble in an aqueous medium into different types of supramolecular nanoassemblies (vesicles, micelles, nanorods, nanospheres, and other kinds of nanoparticles and liquid crystalline structures). This review discusses the supramolecular nanoarchitectures, which can be formed by amphiphilic cyclodextrin derivatives in mixtures with other molecules (phospholipids, surfactants, and olygonucleotides). Biomedical applications are foreseen for nanoencapsulation of drug molecules in the hydrophobic interchain volumes and nanocavities of the amphiphilic cyclodextrins (serving as drug carriers or pharmaceutical excipients), anticancer phototherapy, gene delivery, as well as for protection of instable active ingredients through inclusion complexation in nanostructured media.

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“…It lead us about how structure modifications, such as grafting of electronegative atoms, increase or decrease of lipophilic properties by introducing of hydrophobic substituents, could be made. Recently we have shown the ability of the mentioned calculating methods for a new series of peptidecyclodextrins as suitable host molecules for phase transferring of glucosamine (Seyedi et al, 2010).…”

Section: Molecular Modeling In Designing Of Host Moleculesmentioning

confidence: 99%