Taking the rubbish in the campus of Shanghai Electric Power University as the test object, the single-factor and three-factor five-level orthogonal test design methods were adopted to conduct an experimental study on the cleaning performance of the road cleaner cleaning system and obtain the optimal combination. The mathematical models of the three main factors of driving speed, disc brush speed and roller brush speed and the road sweep rate were established. The influence of each influencing factor and its interaction on the road sweep rate was analyzed, and parameters optimization and test verification were performed. The best combination was found to be a running speed cleaning speed of 5.27 km•h-1 , a disk brush speed of 106.85 r•min-1 , a roller brush speed of 159.86 r•min-1 , and a road cleaning rate of 92.81%. After the test is verified, it is basically consistent with the theoretical optimization results.