Design and preparation of oral jelly candies of acetaminophen and its nanoparticles

Solubility Measurement and Modeling of 9-Phenylcarbazole in Various Organic Solvents at Different Temperatures toward Efficient Process Design of Solvent Antisolvent Precipitation

“…where x is the mole fraction solubility of PCz in different solvents, T represents the absolute temperature, and A, B, and C are empirical parameters. Besides, the root mean square deviation (RMSD) is calculated as follows (4) where N means the number of experimental data and x c and x e represent the calculated mole fraction solubility and the experimental mole fraction solubility, respectively. Table 4 shows the parameters A, B, and C and their respective RMSDs.…”

“…The solvent antisolvent (SAS) purification technique is one of the most common and effective ways for the purification of organic chemicals such as optoelectronic molecular materials, pharmaceutical intermediates, and pigments. − The efficient process design for SAS purification involves finding a solvent where the solid to be purified is very soluble and an antisolvent where the solid has low solubility . Followed by the addition of an antisolvent which is miscible with the solvent, the compound in the mixture solvent reaches saturation and precipitates out of the solvent in the form of solid particles, while the impurities stay in the solution .…”

A novel oral medicated jelly for enhancement of etilefrine hydrochloride bioavailability: In vitro characterization and pharmacokinetic evaluation in healthy human volunteers

“…Purified indium (99.9 %) was used in the reference pan. Each sample (3 mg) was placed in aluminum pans and heated to a temperature of 25–200 °C at a rate of 10 °C/min in an inert nitrogen flow (25 ml/min) ( Hosseini et al, 2022 , Alves et al, 2020 ).…”

“…FTIR analysis of the samples was investigated to explore any possible chemical inter-molecular interactions between ET and each of the used jellifying agents utilizing (Shimadzu, IRAffnity-1, Kyoto, Japan) ( Hosseini et al, 2022 ). FTIR spectra of each sample were determined using the KBr disc technique with spectra between 4000 and 600 cm −1 .…”

Current Innovations in the Development of Functional Gummy Candies

“…Such functional GCs can not only be considered for use by children, but also for adults who are facing various diseases such as mental illnesses. In another study, Hosseini et al [ 83 ] successfully designed anti-fever and analgesic GCs based on gelatin and starch with nano-sized acetaminophen. Cumulative drug release of nanoparticles in GCs was approximately 74% after one day.…”