This chapter delves into the pivotal role of Indigenous Knowledge Systems (IKS) under the framework of ethnoscience in transforming global environmental education. Scholars document the ongoing sixth mass extinction of biodiversity, necessitating urgent collaborative action. Ethnoscience, emerging from joint efforts of pedagogy and UN-led organizations, offers promise in addressing environmental crises. Since the 1990s, ethnoscience studies have highlighted sustainable indigenous management systems. Traditional Environmental Knowledge (TEK), a subset of IKS, imparts sustainable practices and holistic perspectives across generations. TEK fosters global conservation awareness and ecosystem restoration. Building on indigenous cosmovisions like “use the fruits, don't use the wood,” a Model of Integrated Eco-Education (IEE) is proposed. This transdisciplinary model bridges the "knowledge gap" between science and ethnoscience aiming to cultivate eco-conscious global citizens. Efforts target multicultural environmental education in both developing and developed nations, emphasizing students' potential to drive ecological transformation.