Design and performance of a three-dimensional micromixer with curved ribs

Borgohain, Preetirekha; Arumughan, Jyothis; Dalal, Amaresh; Natarajan, Ganesh

doi:10.1016/j.cherd.2018.06.027

Cited by 54 publications

(21 citation statements)

References 36 publications

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“…Alam et al (2014) extended the strategy to compare the mixing performance with different obstruction shapes (e.g., diamond and hexagonal). Hsiao et al (2014) and Borgohain et al (2018) investigated a microchannel with winglet pairs and they confirmed that mixing is enhanced by the longitudinal vortices generated after the winglet pairs. Stroock et al (2002a, b) developed a novel type of T-shaped micromixer with patterned grooves on the bottom of the channel, which is well known and called the staggered herringbone mixer (SHM) and the slanted groove mixer (SGM).…”

Section: Introductionmentioning

confidence: 84%

Optimization of passive grooved micromixers based on genetic algorithm and graph theory

Yoshimura

Shimoyama

Misaka

et al. 2019

Microfluid Nanofluid

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This paper proposes a novel approach for fluid topology optimization using genetic algorithm. In this study, the enhancement of mixing in the passive micromixers is considered. The efficient mixing is achieved by the grooves attached on the bottom of the microchannel and the optimal configuration of grooves is investigated. The grooves are represented based on the graph theory. The mixing performance is analyzed by a CFD solver and the exploration by genetic algorithm is assisted by the Kriging model to reduce the computational cost. The characteristics of the convex and the concave grooves are compared. To balance the global exploration and the reasonable computational cost, this paper investigates three cases with the convex grooves subject to constraint that differs in handling of design variables. In each case, genetic algorithm finds several local optima since the objective function is a multi-modal function, and these optima reveal the specific characteristic for efficient mixing. Moreover, this paper optimizes the micromixer with the concave grooves and reveals the different properties of the mixing. Finally, to guarantee the obtained solutions competitive, the sensitivity analysis is performed to the best solution in each case.

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Section: Introductionmentioning

confidence: 84%

Optimization of passive grooved micromixers based on genetic algorithm and graph theory

Yoshimura

Shimoyama

Misaka

et al. 2019

Microfluid Nanofluid

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“…Passive mixers do not require energy supplied by peripherals, while at the same time they show a substantial increased mixing efficiency compared to diffusion driven process. Several different strategies have been implemented ranging from changing the 2D geometry of the channels [ 11 , 12 , 13 , 14 , 15 ], including obstructions [ 16 , 17 , 18 , 19 , 20 ] or adding different structures to one or more of the channel surfaces [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ], amongst others [ 31 , 32 , 33 , 34 , 35 , 36 ]. The slanted groove mixer (SGM) [ 37 ] exploiting fabricated structures in the ceiling of the microfluidic channels are among the designs that have attracted the most attention.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Mixing Performance Induced by Double Curved Passive Mixing Structures in Microfluidic Channels

Oevreeide

Zoellner²,

Stokke

2021

Micromachines

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Functionalized sensor surfaces combined with microfluidic channels are becoming increasingly important in realizing efficient biosensing devices applicable to small sample volumes. Relaxing the limitations imposed by laminar flow of the microfluidic channels by passive mixing structures to enhance analyte mass transfer to the sensing area will further improve the performance of these devices. In this paper, we characterize the flow performance in a group of microfluidic flow channels with novel double curved passive mixing structures (DCMS) fabricated in the ceiling. The experimental strategy includes confocal imaging to monitor the stationary flow patterns downstream from the inlet where a fluorophore is included in one of the inlets in a Y-channel microfluidic device. Analyses of the fluorescence pattern projected both along the channel and transverse to the flow direction monitored details in the developing homogenization. The mixing index (MI) as a function of the channel length was found to be well accounted for by a double-exponential equilibration process, where the different parameters of the DCMS were found to affect the extent and length of the initial mixing component. The range of MI for a 1 cm channel length for the DCMS was 0.75–0.98, which is a range of MI comparable to micromixers with herringbone structures. Overall, this indicates that the DCMS is a high performing passive micromixer, but the sensitivity to geometric parameter values calls for the selection of certain values for the most efficient mixing.

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“…Generally, these methods can be divided into two categories: active methods and passive methods [4]. Passive methods usually utilize various geometries [5–17] of microchannels and different shapes of obstacles [18–23] or grooves [24–27] placed in microchannels to disturb the laminar flow for vortex formation. Passive methods do not need external energy sources, but the channels of such methods usually need to be designed with complex structures, thereby increasing the fabrication difficulty.…”

Section: Introductionmentioning

confidence: 99%

Electrokinetic‐vortex formation near a two‐part cylinder with same‐sign zeta potentials in a straight microchannel

2020

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Vortex formation near a two-part cylinder with zeta potentials of different values but the same sign under an external DC electric field is numerically investigated in this paper. The cylinder, inserted in a straight microchannel filled with an aqueous solution, is composed of an upstream part and a downstream part. When a DC electric field is applied in the channel, under certain conditions, the vortex will form near the cylinder due to the different velocities of electroosmotic flow generated on the cylinder surface. The numerical results reveal that the larger the velocity difference of electroosmotic flow generated on the two-part cylinder and the smaller the channel width, the more conducive to vortex formation in the channel. In addition, if the zeta potential ratios of cylinder downstream part to upstream part and channel wall to cylinder upstream part are unchanged, the DC electric field strength and the zeta potential value do not affect the pattern of vortices formed in the channel. This study provides a way for vortex formation in microchannels and has the potential application in microfluidic devices.

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Design and performance of a three-dimensional micromixer with curved ribs

Cited by 54 publications

References 36 publications

Optimization of passive grooved micromixers based on genetic algorithm and graph theory

Optimization of passive grooved micromixers based on genetic algorithm and graph theory

Characterization of Mixing Performance Induced by Double Curved Passive Mixing Structures in Microfluidic Channels

Electrokinetic‐vortex formation near a two‐part cylinder with same‐sign zeta potentials in a straight microchannel

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