To achieve posture control and ride comfort (vibration isolation performance) of a robot in unstructured terrain, a novel four-wheel-legged robot (FWLR) with an actively-passively suspension system is first designed. In the suspension system, the active parts are responsible for posture control and the passive parts are responsible for vibration isolation. Then, a closed-loop and decoupled posture control model with 11 DOF are proposed, with which we designed the posture controller with a second-order lowpass filter (SLPF). To test the posture control performance of FWLR in unstructured terrain, both simulation and experiment are carried out, the simulation and experimental results show that the posture angles in unstructured terrain are reduced by 54.65% and 59% on average, respectively. In addition, the frequency response shows that the posture angles are reduced by more than 50% in low-frequency unstructured terrain. Finally, to validate the ride comfort of FWLR, dynamic models with different degrees of freedom (DOF) are established and simulated, and the results present that the ride comfort can be improved with the posture angular acceleration is reduced by 15.83% and 46.7% on average. Generally, with the actively-passively suspension system proposed in this paper, FWLR can be equipped with excellent ride comfort and posture control in unstructured terrain. The research in this paper has potential reference value and practical value for enriching the posture control of robots and vehicles.