Design and operation of a simple continuous‐culture apparatus

Abstract

A versa& and simple continuous-culture apparatus is described. With this apparat,us, independent control of limiting growth factors and other nutrilites is possible and the conditions of each experiment are reproducible. I n view of the synchronized speed of the feeder syringes, flow variation troubles are not encountered. The device allows the performance of growth experiments a t different dilut,ion rates simultaneously in a single run which makes the comparison of the results more reliable. The operation of the device has been tested successfully with a st>rtdy of adenine deaminase induction in yeast.