“…To overcome such control problems, process models and sophisticated algorithms have been developed. Examples include genetic adaptive PI control using internal model control (IMC), adaptive nonlinear feedback control, model predictive control (MPC) based on a dynamic matrix (DMC), model-free learning control (MFLC), Wiener and Hammerstein models, strong acid equivalent control, fuzzy control, ,, neural networks, and hybrid models that integrate multiple control strategies. − Although these proposed models have demonstrated an excellent ability to precisely control pH, most of them have only been examined via simulation. They do not account for potential disturbances and other technical difficulties associated with experimental and physical industrial implementation in real-time manufacturing processes ( e.g ., nonuniformity of the feed stream, flow rate disturbance, and variations in equipment performance).…”