Design and implementation of a low temperature, inductance based high frequency alternating current susceptometer

Riordan, Edward; Blomgren, Jakob; Jonasson, Christian; Ahrentorp, Fredrik; Johansson, Christer; Margineda, Daniel; Elfassi, A.; Michel, S.; Dell'ova, Florian; Klemencic, Georgina M.; Giblin, Sean

doi:10.1063/1.5074154

Cited by 10 publications

(11 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In AC susceptibility vs. temperature measurements at constant excitation frequency, a small amplitude sinusoidal magnetic field is also used, and its frequency can be varied up to about 10 kHz [48]. In a recent paper, an induction-based ACS system that can be used at lower temperatures was designed for frequencies up to the MHz range [49]. Calibration is done in almost the same way as the ACS vs. frequency method using a sample with known dynamic magnetic properties.…”

Section: Ac Susceptometrymentioning

confidence: 99%

“…In addition, in this case, a superimposed DC magnetic field can be applied. In a specific temperature range, the response becomes frequency-dependent, and the ACS results provide information about the magnetic relaxation properties of the MNP ensemble [49][50][51][52][53][54][55]. Thus, measuring the dynamic magnetic properties gives information on the magnetization dynamics in the sample by varying the AC drive frequency (different time scales).…”

Section: Ac Susceptometrymentioning

confidence: 99%

See 1 more Smart Citation

Whither Magnetic Hyperthermia? A Tentative Roadmap

et al. 2021

View full text Add to dashboard Cite

The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.

show abstract

Section: Ac Susceptometrymentioning

confidence: 99%

Section: Ac Susceptometrymentioning

confidence: 99%

Whither Magnetic Hyperthermia? A Tentative Roadmap

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The magnetic response produced by the time-dependent magnetization M(t) of MNPs can be measured by using magnetic sensors such as superconducting quantum interference devices (SQUIDs) [4][5][6], optically pumped magnetometers [7], fluxgates, and giant magnetoresistance sensors [8]. However, compared to other magnetic sensors, the inductive coil is still a preferred sensor in many applications due to its simplicity of operation and design, wide frequency bandwidth, and large dynamic range while providing a cost-effective and straightforward solution [9][10][11][12][13][14]. Owing to these advantages, the inductive coil has been commonly used as the magnetization sensing unit in MNP applications [3,[11][12][13].…”

Section: Introductionmentioning

confidence: 99%

A benchtop induction-based AC magnetometer for a fast characterization of magnetic nanoparticles

et al. 2022

View full text Add to dashboard Cite

In this study, we report a development of a benchtop induction-based AC magnetometer to realize a simple, wideband, and sensitive AC magnetometer for bio-sensing applications and characterization of magnetic nanoparticles (MNPs). We investigate the inductance and parasitic capacitance of six different pickup coil geometries and compare their sensitivity and usable frequency range. In the pickup coil design, the number of turns and coil section separation are varied from 200 to 400 turns, and 1 to 4 sections, respectively. We find that the usable frequency range is greatly affected by the pickup coil’s inductance due to the self-resonance phenomena compared to their parasitic capacitance. A low noise instrument amplifier circuit (AD8429, Analog Devices, USA) was integrated and fabricated on a printed circuit board to amplify the weak signal from the pickup coil. We also implement a generalized Goertzel algorithm to achieve fast signal amplitude and phase extractions at a frequency. The developed magnetometer shows a sensitivity of 10-8 Am2/√Hz at 6 Hz and a frequency range of up to 158 kHz. Using the developed AC magnetometer, we demonstrate the viscosity effect on the frequency response of thermally blocked, single-core nanoparticles (SHP30, Ocean Nanotech, USA) in glycerol solutions. The excitation frequency is swept from 5 Hz to 158 kHz at a field amplitude of 0.55 mTpp within the acquisition time of 5 minutes (51 points). As a result, the viscosity change is confirmed by the peak shifting in the imaginary magnetization curve towards lower frequency values when the wt/V% of the glycerol solution is increased. The hydrodynamic size and the average anisotropy energy ratio σ are estimated to be 60.6 nm and 25, respectively, from the complex AC magnetization. It can be expected that the developed AC magnetometer can be a valuable tool in providing a fast and reliable assessment of MNPs for bio-sensing applications.

show abstract

“…Alternating current susceptometry [1,2] is a traditional probe of magnetic response at applied frequencies ω/(2π) of up to 10 6 Hz [3]. As ω → 0, the isothermal susceptibilty χ T is measured, while historically there was much debate as to whether the high frequency response could be approximated as a quasi-static adiabatic susceptibility, χ S [1], or a quasi-static isolated (or quantum adiabatic) susceptibility, χ I [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Experimental measurement of the isolated magnetic susceptibility

et al. 2021

Self Cite

View full text Add to dashboard Cite

The isolated susceptibility χI may be defined as a (non-thermodynamic) average over the canonical ensemble, but while it has often been discussed in the literature, it has not been clearly measured. Here, we demonstrate an unambiguous measurement of χI at avoided nuclear-electronic level crossings in a dilute spin ice system, containing well-separated holmium ions. We show that χI quantifies the superposition of quasi-classical spin states at these points, and is a direct measure of state concurrence and populations.

show abstract

Design and implementation of a low temperature, inductance based high frequency alternating current susceptometer

Cited by 10 publications

References 23 publications

Whither Magnetic Hyperthermia? A Tentative Roadmap

Whither Magnetic Hyperthermia? A Tentative Roadmap

A benchtop induction-based AC magnetometer for a fast characterization of magnetic nanoparticles

Experimental measurement of the isolated magnetic susceptibility

Contact Info

Product

Resources

About