Design and evaluation of a novel portable erythema‐melanin‐meter

Abstract

The data suggest that the technique has a substantial potential as a method of pre-treatment diagnostics for photochemical and photothermal procedures.

Reflectance spectroscopy for noninvasive evaluation of hair follicle stage

“…Actually, other wavelengths, such as 650 and 710 nm could also be effective for the evaluation of melanin. 21 The melanin value during a complete hair follicle change is in the range of 440 to 730, which is consistent with the instructional melanin range of brown skin, dark hair (150 to 500) and black skin (600 to 999) in the MX® 18 instructions. The melanin in the anagen skin is 1.7 times that of telogen skin, which also agrees with the melanin content of 1.7 to 3.2 times in black hair compared with light brown hair.…”

Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE)

“…The importance of the measurement of skin temperatures to study thermal injury was recently emphasized in a study [15] which also used a thermal camera to study adverse effects in the context of LHR. Alternative methods to quantify epidermal melanin concentration use purely optical measurement techniques [6,8,10,16] through reflectance spectroscopy but not by correlation with actual temperature measurements. An obvious advantage of optical reflectance methods is that no laser device is required, unlike a diagnostic PPTR measurement.…”

“…A number of objective diagnostic methods to quantify individual skin melanin concentration have been demonstrated including photo-acoustics [6], visible reflectance spectroscopy [7][8][9], and colorimetry [10]. Although these methods typically provide information such as the epidermal absorption coefficient, epidermal melanin concentration or epidermal thickness, such information is of limited use to the clinician unless the physician knows how a certain RE relates to expected adverse effects.…”

Objective Assessment of Dermatitis Following Post-operative Radiotherapy in Patients with Breast Cancer Treated with Breast-conserving Treatment

“…In most previous studies, the extent of erythema was determined with subjective means, such as visual inspection. Some attempts to establish objective measurements have been reported in the literature [4,11,12,14,21,22], i.e., visual reflectance spectroscopy and determination of a high-frequency dielectric constant [15]. These results have prompted the present study, which is concerned with the development of an objective assessment method for skin reaction that can be used by multiple observers, especially when a multi-institute trial is involved.…”